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App Notes

Results 1291–1300 of 1416

Ligation Efficiency of NxSeq® Sample Preparation Using the Gilson PIPETMAX® 268

| Contributed by Gilson

This application note describes the results of the ligation efficiency of manual library preparation versus automated library preparation.

Enhancing aroma profiling of wine with GC–TOF MS

| Contributed by Markes International Ltd

This Application Note shows that BenchTOF time-of-flight mass spectrometers, coupled with GC, can provide a high-performance solution for the detection and quantitation of aroma compounds in wine extracts.

Investigating Matrix Interference in Analysis of Antiarrhythmic Cardiac Drugs in Plasma

| Contributed by Supelco

In this study the impact of matrix interference is investigated with respect to precision and accuracy of antiarrhythmic cardiac drugs from plasma samples.

Extraction of Mycophenolic Acid (MPA) and Mycophenolic Acid Glucuronide (MPAG) from Serum Using ISOLUTE® SLE+ prior to LC-MS/MS

| Contributed by Biotage

This application note describes the extraction of the immunosuppressant drug mycophenolic acid and its metabolite mycophenolic acid glucuronide from fortified serum using ISOLUTE SLE+ in a 96-well plate format.

UHPLC Column Protection Dramatically Extends UHPLC Column Performance and Lifetime

| Contributed by Phenomenex

UHPLC columns can significantly improve chromatographic separations, but they also present unique challenges. Once the system components are optimized, perhaps your greatest concern is protecting the column from the damaging effects of microparticulates and sample contaminants.

LC/MS/MS Analysis of Immunosuppressants from Whole Blood

| Contributed by Phenomenex

LC/MS/MS analysis of immunosuppressants from whole blood often involves complex and/or expensive cleanup methods.

Analyzing Pharmaceutical Tablet and Capsule Excipients by Gel Permeation Chromatography (GPC) using Phenogel™ Columns

| Contributed by Phenomenex

Several classes of excipients such as binders, coatings, and suspending agents were run on individual fixed pore size or mixed bed GPC columns to show how certain tablets and capsules compare with standards.

A Rapid Screening Method for Analysis of Multi-Class Antibiotics from Ground Meat (sausage) using QuEChERS and LC/MS/MS

| Contributed by Phenomenex

A rapid and sensitive multi-class screening method for the detection of multiple classes of antibiotics in ground meat samples at maximum residue limit levels defined by Commission Regulation (EU) No 37/2010, using LCMSMS and QuEChERS.

A Fast and Effective Approach to Analyzing Hormones in Drinking Water Using SPE and LC/MS/MS

| Contributed by Phenomenex

An optimized steroid hormone analysis from drinking water by LC/MS/MS, reducing analysis time from 50 minutes down to 15 minutes while maintain excellent linearity (0.99 R2 value or greater for each compound) and low minimum reporting level (MRLs)

Fast, Accurate Analysis of Polybrominated Diphenyl Esters (PBDEs) In A Single Run, Including BDE-209

| Contributed by Phenomenex

A new HRGC–HRMS method and technology provides quantitation of toxic PBDE congeners with short run times and includes the quantitation of BDE-209 in a single analytical run.

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