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March 2021 Issue of The Analytical Scientist

This month, our cover feature explores the proteomics battlegrounds in the fight against COVID-19 and provides expert insight on some of the developments we can expect in the future. We also get an inside view on the hunt for life on Mars – more specifically, the analysis of sulfates in Martian soil – and Michael Kurczy and Alison Hulme discuss their forays into the field of subcellular drug imaging. Elsewhere, we hear about the importance of ethics in clinical proteomics, Isabelle Kohler shares her thoughts on role models in academia, and we sit down with Davy Guillarme to talk about his work using HPLC for pharmaceutical applications.

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Articles featured in this issue

Business & Education

Women in Analytical Chemistry

A selection of key figures from our field’s history

Fields & Applications Liquid Chromatography

Scouting for Antimicrobial Morsels

| Lauren Robertson

Tracking down traces of multiclass antibiotics in our food

Fields & Applications Mass Spectrometry

The Tree of (Solar) Life

| Lauren Robertson

Researchers have used radioactive carbon in tree rings to look back through a millennium of solar activity

Fields & Applications Spectroscopy

Spectroscopy on the Brain

| Matthew Hallam

Could a combined spectroscopy approach prove a secret weapon in the fight against glioblastoma?

Fields & Applications Mass Spectrometry

Image of the Month: Old Mold

| Lauren Robertson

Discovery of the oldest terrestrial fossil could rejig our planet’s timeline

Fields & Applications Mass Spectrometry

Target Practice

| Matthew Hallam

A new native MS method may allow us to identify binding targets for any small molecule

Business & Education Education

Bringing Employability to the Classroom

| Fiona Ponikwer, Bhavik Patel

Bhavik Patel and Fiona Ponikwer argue that work-integrated learning should be a key tool for improving the employability of graduates

Business & Education Education

Mind the (Gender) Gap

| Isabelle Kohler

Isabelle Kohler discusses the impact of role models in analytical science in the run up to International Women’s Day

Fields & Applications Clinical

Ethical Considerations in Clinical Proteomics

| Sebastian Porsdam Mann, Philipp Geyer, Peter Treit, Matthias Mann

Kickstarting important conversations about ethics in a thriving field

Fields & Applications Mass Spectrometry

The Call of Coronal Duty

| Lauren Robertson, Perdita Barran, Jeroen Demmers, Manfred Wuhrer

Jeroen Demmers, Perdita Barran and Manfred Wuhrer walk us through the proteomics battlegrounds in the fight against COVID-19

Techniques & Tools Microscopy

Let There be Light!

| Sponsored by Bruker

Catching up with the experts behind the award-winning LUMOS II FTIR microscope

Fields & Applications Pharma & Biopharma

Getting Lipid Nanoparticle Production Right

| Sponsored by Knauer

KNAUER’s Matthias Luebbert discusses the company’s recent move into lipid nanoparticles

Fields & Applications Spectroscopy

In Search of Sulfates - and Aliens!

| Juan Manuel Madariaga, Duncan Stacey

Juan Manuel Madariaga and Duncan Stacey discuss the hunt for sulfates on the Red Planet

Fields & Applications Mass Spectrometry

Seeing the Smaller Picture

| Matthew Hallam

Michael Kurczy and Alison Hulme discuss their forays into the field of subcellular drug imaging

Business & Education Business

From Big Pharma to New Green Horizons: Lessons Learned with Ross Burn

| Ross T. Burn

Ross Burn presents the story behind his career, including setting up a company on process chemistry and his views on industry 4.0.

Detailed glycosylation analysis of therapeutic enzymes using µPAC™ capLC-MS and all-ion fragmentation

| Contributed by Pharma Fluidics

Find out how the PharmaFluidics’s µPAC™ capLC column provides information on glycosylated peptides in the complex LCMS digest of a therapeutic enzyme.

Detection of residual pesticides on fruits and vegetables using Portability™ miniature mass spectrometer

| Contributed by Bayspec

Mass spectrometry can be now deployed for onsite pesticide screening in real time.

Fields & Applications Liquid Chromatography

Biologics Explorer

Davy discusses his work in HPLC for pharmaceutical applications and influential mentors

Other issues of 2021