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May 2019 Issue of The Analytical Scientist

In this issue, we asked you to tell us about your most longed-for developments in mass spectrometry - see the results in our MS wish list. Plus, we explore the chemistry of Tennessee Whiskey, lab-on-a-chip devices for diagnostic applications, unified chromatography, top tips for chemistry careers and the rise of hyper-fast gas chromatography. Finally, we sit down with David Clemmer to discuss ion mobility and life beyond the breakthrough.

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Articles featured in this issue

Techniques & Tools Technology

Image of the Month

| Charlotte Barker

Close-up of a low-power, ultra-high-speed GCxGC system that's small but packs a punch to the tune of 50 compounds per second peak capacity.

Business & Education Business

Power for Change

| Charlotte Barker

Nominations are now open for this year's power list - a celebration of the heroes of analytical science.

Fields & Applications Gas Chromatography

As Smooth as Tennessee Whiskey

| Ryan De Vooght-Johnson

What makes Tennessee whiskey so special? Researchers at the University of Tennessee set out to investigate using SAFE, SIDA and GC-olfactometry.

Techniques & Tools Spectroscopy

Now Streaming: Spectral Simplification

| Jonathan James

An algorithm originally developed for Netflix shows promise to improve the diagnostic applications of Raman spectroscopy.

Fields & Applications Metabolomics & Lipidomics

Ice Cream Bean Dream

| Ryan De Vooght-Johnson

What's the scoop? Metabolomic data from ice cream bean trees highlight the diversity of tropical ecosystems.

Fields & Applications Forensics

Splitting Hairs: Ingestion or Contamination?

| Matthew Hallam

Traditional testing of hair for drug use has struggled to differentiate genuine drug ingestion from external contamination - until now.

Techniques & Tools Clinical

Game of Exosomes

| Luke Turner

New lab-on-a-chip device that identifies tumor exosomes in blood samples may provide a noninvasive diagnostic tool for cancer patients.

Business & Education Gas Chromatography

Storming the Fort

| Charlotte Barker

With ISCC and GCxGC 2019 looming, we spoke to co-chair Kevin Schug about what to expect from this year's program.

Techniques & Tools Mass Spectrometry

MS and NMR - the Perfect Couple?

| Ricardo M. Borges

MS and NMR represent two powerful individual tools - but is a combination of both the most powerful way forward?

Business & Education Professional Development

Expect the Unexpected

| Yong Guo

Scientific careers are inherently unpredictable, but there are a number of steps we can take to be prepared.

Techniques & Tools Preparative/Process Chromatography

Unifying Chromatography on All Fronts

| Lydia Kisley

Unifying separation disciplines may provide a powerful approach for addressing future problems - we explore the possibility with Lydia Kisley.

Techniques & Tools Liquid Chromatography

Technology with a Real Edge

| Sponsored by Pharma Fluidics

Johan Devenyns, CEO of PharmaFluidics, answers our questions on their micro-chip chromatography technologies including the μPAC.

Techniques & Tools Mass Spectrometry

MS Wish List

| Renã Robinson, Donald Chace, Timothy Garrett, Benjamin Garcia, Elena Stashenko

We asked MS users what developments they would most like to see in the field and why - check out their answers in our MS wish list.

Techniques & Tools Gas Chromatography

Hyper-Fast GC

| Peter Boeker

From beginner's luck to modern expertise, Peter Boeker takes us through his journey with field flow thermal gradient gas chromatography.

Techniques & Tools Liquid Chromatography

Detecting Change

| Sponsored by Agilent Technologies

Lester Taylor of Agilent Technologies discusses the results of our recent survey on trends in liquid chromatography.

Business & Education Education

Everything You Wanted to Know About a Career in Chemistry* - Part II (*But Were Afraid to Ask)

| Peter Kissinger

Peter Kissinger, professor and entrepreneur, shares his wisdom on building a successful career in chemistry.

Evaluation of mAb ADCC Activity through Fc Receptor Affinity Chromatography

| Contributed by Tosoh

Antibody-dependent cell-mediated cytotoxicity is a mechanism of action of anti-tumor antibodies in which the Fcy receptor (FcR) plays a key role.

Direct Analysis of Intact Proteins using the ADVION TOUCH EXPRESS™ Open Port Sampling Interface (OPSI) with the ADVION expressionL Compact Mass Spectrometer

| Contributed by Advion

In this application note, the Advion Touch Express Open Port Sampling Interface (OPSI) is coupled with the Advion expressionL Compact Mass...

Generic Analyses of Different Monoclonal Antibodies with RP-(U)HPLC

| Contributed by YMC

This application note shows how to achieve robust chromatographic results for commercially available MAbs.

Business & Education Mass Spectrometry

Upward Mobility

| Frank van Geel

Ion mobility pioneer David Clemmer tells us how he went from studying music to answering the big questions in science.

Other issues of 2019