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June 2015 Issue of The Analytical Scientist

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Articles featured in this issue

Techniques & Tools Technology

The Big Picture

| Rich Whitworth

In the quest for increased sensitivity or higher resolution, let’s not lose sight of our objectives.

Techniques & Tools Spectroscopy

Fingerprinting mAbs

| Rich Whitworth

Using NMR spectroscopy to investigate the structure of monoclonal antibodies

Techniques & Tools Mass Spectrometry

Bio Surfing

| Stephanie Sutton

How to compare and contrast biosensor performance

Fields & Applications Food, Beverage & Agriculture

To Eat or Not to Eat

| Stephanie Sutton

You know the meat that’s been sitting in your fridge for a while... is it still safe?

Fields & Applications Genomics & DNA Analysis

Advancing Paper Diagnostics

| Stephanie Sutton

Can a stacking flow system offer more uniform results for immunoassay saliva tests?

Fields & Applications Clinical

Skin Deep Biosensing

| Stephanie Sutton

Simultaneous monitoring of multiple metabolites – with a chip beneath the surface of your skin

Fields & Applications

The Art of Analysis

| Rich Whitworth

In August, The Analytical Scientist will publish a special issue celebrating the very best images in the field of analytical science. And you have the chance to submit an image that defines your work.

Fields & Applications Liquid Chromatography

Bridging the Biomarker Gap

| Rainer Bischoff

How to bring better diagnostic tests to the market to benefit patients.

Fields & Applications Mass Spectrometry

Capture Recapture

| Zuzana Gajdosechova

Isotope dilution mass spectrometry analysis highlights effective interdisciplinary collaboration – and its legacy should be at the forefront of modern research.

Techniques & Tools Technology

Enlightening LEDs

| Mirek Macka

The 2014 Nobel Prize in Physics, awarded “for the invention of efficient blue light-emitting diodes,” has put LEDs under the spotlight, particularly as a stable, robust and efficient light source in analytical sciences.

Techniques & Tools Spectroscopy

Driving SERS into the Clinic

| Mustafa Culha

Raman spectroscopy has evolved into a powerful characterization technique for many applications. What more needs to be done to make it effective in clinical analysis?

Fields & Applications Liquid Chromatography

Pushing the Limits of Liquid Chromatography

We must inspire creative minds to keep LC moving forward

Fields & Applications Liquid Chromatography

Have We Really Peaked?

| James Jorgenson

Liquid chromatography is not just an analytical tool for today, it offers a great deal for the future.

Fields & Applications Liquid Chromatography

Marching Ever Onward

| Gert Desmet

The evidence contradicts those who say liquid chromatography has fully matured.

Techniques & Tools Liquid Chromatography

Marking Progress

| Monika Dittman, Fabrice Gritti

Monika Dittman (Agilent Technologies) and Fabrice Gritti (Waters) offer a manufacturer point of view on the practical limits of LC.

Techniques & Tools Pharma & Biopharma

Finding Humanity in Science

| Rich Whitworth

What drives someone to throw aside selfish pursuits to focus on projects with true philanthropic impact? Here, the winners of the 2015 Humanity in Science Award provide their answers.

Techniques & Tools Preparative/Process Chromatography

The (not so) EZ Journey to Improved GC Methods

| Jaap de Zeeuw, Jack Cochran

In 2014, The Analytical Scientist Innovation Awards recognized our new and simplified EZGC® method development software. Here, we explore the complex roots that led to its creation.

Fields & Applications Mass Spectrometry

Protein Powerhouse

| Rich Whitworth

Sitting Down With... Ruedi Aebersold, Deputy Head, Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Switzerland

Techniques & Tools Gas Chromatography

Reinventing GC-MS

| Joshua Coon

At ASMS 2015, GC-Orbitrap™ technology was unleashed onto an expectant analytical community. Here’s the backstory.

Fields & Applications Sample Preparation

Accelerating the deformulation workflow for oral solid dosage forms

In this white paper we examine the deformulation workflow, demonstrating the value of the technique of Morphologically Directed Raman Spectroscopy (MDRS) within this context. Case studies illustrate the relevance of MDRS data.

Fields & Applications Sample Preparation

Measurements of absolute molecular weight of synthetic polymers

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

Fields & Applications Sample Preparation

Optimizing Small Volume of Block Co-Polymers Used for Enhanced Oil Recovery

Read how DLS-based optical microrheology can be used to determine the rheological behavior of polymer solutions and the impact of tracer particle chemistry on the measured microrheological response.

Other issues of 2015