UHP-SEC Analysis of Immunoglobulins with TSKgel UP-SW3000
September 16, 2015
Antibody therapeutics are dominating the biopharmaceutical market. In 2013, six of the top ten global drug brands were monoclonal antibodies (mAbs). The characterization of these complex biomolecules is a major challenge in process monitoring and quality control. The main product characteristics to be monitored by chromatography are aggregate and fragment content, glycosylation pattern and charged isoforms.
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