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September 2015 Issue of The Analytical Scientist

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Articles featured in this issue

Fields & Applications

How Do You Measure Success?

| Rich Whitworth

Opening Pandora’s box with a seemingly simple question.

Techniques & Tools Mass Spectrometry

Alzheimer’s Analytics

| Michael Schubert

Predictive biomarkers in saliva may yield a simple, noninvasive diagnostic test

Techniques & Tools Mass Spectrometry

Do Bears Also Eat in the Woods?

| Stephanie Sutton

Laser ablation and ICP-MS has the answer

Techniques & Tools Spectroscopy

(Don’t) Fade to Grey

| Rich Whitworth

Synchrotron-based FTIR, XRF, and XANES probe Matisse’s jaded yellow

Techniques & Tools Spectroscopy

Quantum Leap in Real-time Spectroscopy

| Stephanie Sutton

Continuous monitoring of chemical products with an innovative matchbox-sized laser

Fields & Applications Mass Spectrometry

Splitting Hairs

| Bryn Flinders

Despite the recent bad press, cutting-edge analytical techniques are transforming the field of hair analysis

Fields & Applications Clinical

Simpler Blood Sampling

| Rich Whitworth

hemaPEN aims to rewrite the textbook for disease screening, therapeutic drug monitoring and medical research

Techniques & Tools Metabolomics & Lipidomics

There’s More to Life Than DNA

| Kévin Contrepois, Michael Snyder

Genomics often steals the headlines, but could metabolomics be the true deliverer of personalized medicine?

Fields & Applications Food, Beverage & Agriculture

Future Food Forensics

| Dietmar Knopp

By Dietmar Knopp, Professor of Applied Biochemistry and Head of Group ‘Bioanalytics’ at the Chair of Analytical Chemistry, Institute of Hydrochemistry, Technische Universität München, Munich, Germany.

Techniques & Tools Food, Beverage & Agriculture

Organoarsenical Seafood Cocktail

| Jörg Feldmann

Are we analyzing the right arsenic species or are organoarsenicals actually wolves in sheep’s clothing?

Techniques & Tools Spectroscopy

The Road to Complete Chemical Analysis

| Rick Russo

New analytical technology combinations promise simultaneous solvent-free measurement of every element on the periodic chart. And that’s something worth shouting about.

Techniques & Tools Sample Preparation

The Virtues of Graphene

| Constantine Stalikas

In what should be our constant endeavor to improve sample preparation, we must look to new materials – and focus on bending them to our own needs.

Techniques & Tools Mass Spectrometry

Unraveling the Cannabinome

| Scott Kuzdzal and William Lipps

Legalized cannabis is an exploding market that offers exciting opportunities – and challenges – for analytical scientists.

Techniques & Tools Metabolomics & Lipidomics

Optimizing the Search for the Unknown

| Gerhardus(Ad) de Jong

Non-targeted profiling is progressing in many application areas, including food, drugs, environmental, proteomics and metabolomics – but how can we measure the suitability of our own methods?

Techniques & Tools

Your Local School Needs You

| Robert Thomas

Professionals in the fields of science, technology, engineering, and mathematics – STEM – have great potential to boost scientific literacy in schools. Can you make time to pass on years of experience and educate the next generation?

Techniques & Tools

Your Standards Organization Needs You

| Taco van der Maten

Analytical scientists play an important role in the standard setting process. Are you involved?

Techniques & Tools Liquid Chromatography

Bioengineering a Quantitative Future

| Rich Whitworth

Sitting Down With... Amy Herr, Lester John & Lynne Dewar Lloyd Distinguished Professor of Bioengineering, University of California, Berkeley, USA.

Fields & Applications Spectroscopy

Spectroscopy’s New Role in Document Security

| Cicely Rathmell

Banknotes, passports and professional licenses have high value and are at risk for counterfeiting, tampering and forgery.

Fields & Applications Pharma & Biopharma

UHP-SEC Analysis of Immunoglobulins with TSKgel UP-SW3000

| Sponsored by Tosoh

Antibody therapeutics are dominating the biopharmaceutical market. In 2013, six of the top ten global drug brands were monoclonal antibodies (mAbs).

Fields & Applications Mass Spectrometry

Marching Forward with Food Analysis

| Mike Dickinson

The analytical aspect of the food industry has changed significantly over the last decade – mainly because of advances in technology. From pesticide residues to metabolomic approaches, the field is now more exciting than ever.

Fields & Applications Mass Spectrometry

Making Solutions Routine

| Sponsored by Thermo Fisher Scientific

The Pesticide Explorer Collection offers complete workflow-driven solutions to meet the challenges of modern pesticide residue analysis. Are you ready for a premium solution?

Fields & Applications Mass Spectrometry

Attaining Accurate Authentication

| Jana Hajšlová

As fraudsters become increasingly knowledgeable and adept, authentication of food and beverages becomes more and more challenging. I was keen to see if GC-Orbitrap technology represented a new tool in the defense of food safety and quality – and Scotland’s centuries-old whisky industry.

Fields & Applications Sample Preparation

Understanding the effect of polymer structure on its bulk properties

Four different polymers are analyzed by GPC/SEC to investigate the effect of molecular weight, dispersity and molecular structure on the final properties of the polymer.

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20...

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. This allows OmniSEC to follow the injections performed by a Waters SEC system and to synchronize data collection. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

Size Exclusion Chromatography / Gel Permeation Chromatography: An Introduction in 30 Minutes

GPC/SEC is mainly used for the characterization of macromolecules including synthetic and natural polymers (including polysaccharides) as well as proteins or RNA/DNA. This white paper provides an introduction to the technique in 30 minutes.

Fields & Applications Sample Preparation

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Other issues of 2015