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December 2021 Issue of The Analytical Scientist

Find out which 15 trailblazing technologies cut the mustard with our judges in this year’s Innovation Awards! This issue also features an interview with “Analytical Neuroscientist,” Jonathan Sweedler, who was recently ranked first on our annual Power List – for the second time. Sticking with the life sciences, Michael McGinley walks us through the Wild West of Oligonucleotide Analytics, where survival requires a good understanding of both chemistry and biology; and Albert Heck discusses how native MS may help rewrite the textbooks and immunology – and even life itself. Elsewhere, Norbert Jakubowski discusses how to take ICP-MS to the next level, and Calum Preece reviews the role of stable isotope analysis in the ongoing search for evidence of our changing environment. Finally, find out how gas spectroscopy could solve critical clinical challenges in respiratory diagnostics and how NMR spectroscopy could help scientists in the fight against antifungal resistance.

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Articles featured in this issue

Fields & Applications Spectroscopy

The Phantom Lung

| Lauren Robertson

How a gas spectroscopy technique could solve critical clinical challenges in respiratory diagnostics and treatment

Fields & Applications Mass Spectrometry

Dating the Big Tree

| Lauren Robertson

Accelerator MS used to radiocarbon date the historic Big Tree at Victoria Falls, Zimbabwe

Fields & Applications Spectroscopy

A Closer Look at the Fungal Armor

| Lauren Robertson

NMR spectroscopy could help scientists in the fight against antifungal resistance

Fields & Applications Spectroscopy

Casting Light into the Dark Unknowns of the Cosmos

| Lauren Robertson

Could NASA’s Roman telescope help scientists answer some of the most perplexing questions about the universe?

Techniques & Tools Spectroscopy

ToF-SIMS: A Secret Forensics Weapon?

| Lauren Robertson

How a new approach to imaging could help forensics scientists retrieve fingerprints from tricky bullet casings

Fields & Applications Metabolomics & Lipidomics

Popular Reflections: The Rise and Rise of Metabolomics

| James Strachan

In 2018, Martin Giera, Mary E. Spilker and Gary Siuzdak shared their love of a special field in “Metabolomics: the Superglue of Omics”

Techniques & Tools Mass Spectrometry

ICP-MS: Taking the “Gold Standard” to the Next Level

| Norbert Jakubowski

What's next for ICP-MS?

Fields & Applications Environmental

Stable Isotopes in an Unstable Climate

| Calum Preece

The ongoing search for evidence of our changing environment

Business & Education Data Analysis

No Prize for Second Place?

| Meriem Gaida

We should all focus on data quality by sticking to the four Cs: consistency, correctness, completeness, and credibility

Fields & Applications Pharma & Biopharma

Taming the Wild West of Oligonucleotide Analytics

| Michael McGinley

In the Wild West of Oligonucleotide Analytics, survival requires a good understanding of both chemistry and biology

High sensitivity screening of antineoplastic drugs using a 1 mm diameter YMC-Triart C18 UHPLC column

| Contributed by YMC

In this application note, the screening of 6 antineoplastic drugs is shown

Fields & Applications Translational Science

The Analytical Neuroscientist

| James Strachan

We sit down with "The Analytical Neuroscientist," Jonathan Sweedler

Fields & Applications Mass Spectrometry

Talkin’ ‘Bout a (Protein) Revolution

| Albert Heck

Albert Heck believes native MS will help rewrite the textbooks on immunology, and increase our knowledge of our wellness, health, and the planet