5 Key Takeaways

• 1

  New indicators of Alzheimer's risk may be linked to brain blood flow and oxygen delivery, as per a study using noninvasive cerebrovascular measurements.

• 2

  Researchers combined ultrasound and optical measurements to identify cerebrovascular indicators that align with established Alzheimer's neuroimaging markers.

• 3

  Higher cerebrovascular indicator values were associated with lower amyloid burden and larger hippocampal volume, indicating lower Alzheimer's risk.

• 4

  Participants with mild cognitive impairment or dementia exhibited poorer cerebrovascular indicators compared to cognitively normal adults.

• 5

  The study suggests that noninvasive cerebrovascular measurements could complement existing imaging approaches for Alzheimer's disease.