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Application Notes by YMC

LC-MS/MS Analysis of Sphingophospholipids Using Metal-Free Columns

| Contributed by YMC

LC analyses of sphingophospholipids often show peak tailing and loss of sensitivity and reproducibility.

Fast and Easy Achiral & Chiral Analysis of Cannabinoids

| Contributed by YMC

Two fast methods for separating different cannabinoids using YMC-Triart C18 UHPLC column and YMC’s Core-Shell Meteoric Core C18 column.

SEC Analysis of MAb Fragments with Increased Throughput and High Resolution

| Contributed by YMC

This app note shows the analysis of intact MAb and digested fragments Fab dimer, Fc and Fab using the UHPLC compatible YMC-Pack Diol-200 column.

Generic Analyses of Different Monoclonal Antibodies with RP-(U)HPLC

| Contributed by YMC

This application note shows how to achieve robust chromatographic results for commercially available MAbs.

HPLC Analysis of Drug-to-Antibody Ratio (DAR) Using BioPro HIC BF

| Contributed by YMC

Antibody-Drug Conjugates (ADCs) are highly potent biopharmaceutical drugs.

Reaction monitoring of Antibody-Drug-Conjugates (ADCs) Using YMC´s BioPro HIC BF

| Contributed by YMC

Drug-antibody ratio (DAR) of antibody-drug conjugates (ADCs) is important for their therapeutic efficacy and pharmacokinetics.

RP Analyses of Monoclonal Antibodies Using High Temperatures YMC

| Contributed by YMC

Monoclonal antibodies (MAbs) are immunological active proteins, which bind specifically to certain cells or proteins. This will stimulate the immune system to attack those targets.

HPLC Analysis of Oligonucleotides Using YMC’s Non-porous AEX Columns

| Contributed by YMC

A method for the determination of oligonucleotides using YMC-BioPro QA-F has been developed by YMC. 3 application examples are presented here.

Techniques & Tools Liquid Chromatography

YMC-Triart C18: Amino acids with 100% aqueous mobile phase

| Contributed by YMC

For analysis of very polar compounds the option to work with 100% aqueous mobile phases is required.

Techniques & Tools Liquid Chromatography

Detect the small but subtle differences of fatty acid isomers!

| Contributed by YMC

Analyse fatty acid isomers with YMC-Triart C18 ExRS without derivatisation in less than 6 minutes! Fatty acids have a well documented effect on health.

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