5 Key Takeaways

• 1

  Raman spectroscopy offers rapid, label-free molecular fingerprinting of viruses and host responses, enhancing virology diagnostics.

• 2

  Enhanced Raman techniques like SERS, TERS, and CARS improve sensitivity and resolution for real-time detection of viral interactions.

• 3

  Raman-based methods have shown rapid detection capabilities for influenza and SARS-CoV-2 with high accuracy in complex samples.

• 4

  Research focus is skewed towards high-impact viruses, leaving high-risk pathogens like Lassa and Marburg underexplored.

• 5

  Technical challenges such as weak signal intensity and regulatory hurdles hinder the clinical translation of Raman spectroscopy.