Paola Picotti
The Power List 2014
Paola Picotti
Assistant Professor, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Calling: “Proteins are fascinating molecules. They supervise basic functions in cells through a variety of complex structures and interactions, which makes the development of methods for their analysis challenging and stimulating.”
Regret: “No. I would still opt for a strong background in chemistry and a focus on method development.”
Emphasis: “We study the effects of intracellular protein misfolding and aggregation using novel quantitative and structural proteomics approaches.”
Triumph: “The development of a method to analyze protein structural changes directly in biological samples and on a large scale.”
Hope: “Exploiting the power of the novel methods we developed to advance our knowledge on protein misfolding and support the identification of therapeutic strategies for protein misfolding diseases; for example, Parkinson’s disease.”
Advice: “Follow only what interests you, entertains you, and tickles your curiosity. Expose yourself to different mindsets and scientific backgrounds.”