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Techniques & Tools Mass Spectrometry

Antimicrobial Abuse

| Richard Stadler

In response to the over-dependence and misuse of antimicrobials in food producing animals, ... analytical testing and surveillance is being stepped up. Here, current best practice and likely directions for monitoring antimicrobials is described.

Techniques & Tools Technology

The Tools of Proteomics

| Norm Dovichi, Amanda Hummon

The proteome, which is the set of proteins expressed by a genome, cell, tissue or organism at a given time ... presents immense analytical challenges – but offers substantial rewards. Here, current approaches to proteomics, their strengths and their shortcomings, are explored.

Fields & Applications Sample Preparation

Confronting Concerns

| Sangeeta Tanna, Graham Lawson

With many potential benefits, it is easy to understand the drive to develop systems and methods acceptable to the regulatory authorities.

Fields & Applications Genomics & DNA Analysis

Principal Drivers for DBS Research

| Sangeeta Tanna, Graham Lawson

It is now recognised that regarding a child as a scaled down adult to calculate a medicine dose may not be appropriate.

Fields & Applications Mass Spectrometry

Dried Blood Spot 101

| Sangeeta Tanna, Graham Lawson

Introduced by Robert Guthrie in the 1960s, dried blood spot (DBS) sampling involves taking small drops ... of blood from either a finger prick (or heel prick in neonates) and depositing them on specially manufactured absorbent card where they are allowed to dry. Once dry, DBS cards can be readily transported by post for analysis since the components of the blood remain unchanged for several days, even at room temperature. For analysis, a portion of the blood spot is removed from the card and placed in a solvent to extract the analyte(s) of interest.

Fields & Applications Pharma & Biopharma

The S-Word and US Research

| Bill Kelly

What short- and long-term impact will sequestration have on the US scientific community?

Fields & Applications Micro/Nano-scale

Excitement on the Smallest Scale

| Steve Carrington

Microrheology is in its early stages, but it has the potential to expand the range and enhance the application of rheological characterization.

Techniques & Tools Mass Spectrometry

Instrumental to Success

| Steve Cohen

An illustration of how working with customers throughout development increases the effectiveness of ... new products.

Techniques & Tools Data Analysis

Yes, We Have a Quality Manager

| Peter Kootstra

Why lab SOPs are cumbersome and often ignored, and what can be done to improve them ...

Fields & Applications Chemical

Talking of Heritage...

| Rich Whitworth

Recording the impact of chemistry on society, the Chemical Heritage Foundation's participation in Pittcon adds valuable, historical depth.

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