Simplifying Explosives Analysis for Evolving Soil Regulations
January 29, 2026
How Agilent developed a new workflow to tackle Germany’s updated soil regulations
2 min read
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Liquid Chromatography
GLP-1 Analysis: Riding the Wave of Peptide Innovation
By Amanda M. Guiraldelli, Piotr Alvarez, Koen Sandra
January 26, 2026
The remarkable commercial success of GLP-1 receptor agonists is fueling investment, accelerating science, and creating new analytical challenges. Here, we outline the hurdles these peptides present, explore methods for impurity profiling and structural characterization, and consider strategies to keep pace with this fast-moving field.
12 min read
A Foundation for Revolutionary Separation Performance?
By Fabrice Gritti
December 18, 2025
Bo Zhang’s new strategy for the precise manufacturing of LC microspheres may allow scientists to conduct the experiments needed to make breakthroughs in column performance
5 min read
How to Fingerprint Cell Culture Media
By Jude Lakbub
December 17, 2025
Understanding cell culture media components is crucial – and LC-MS fingerprinting can help.
4 min read
Formic Acid Boosts LC-MS Metabolomics Sensitivity
November 20, 2025
A small tweak to sample prep – formic acid pretreatment – enhances LC–MS sensitivity and metabolome coverage without compromising reproducibility
2 min read
How Tap Water Sparked a Breakthrough in Ion-Assisted Chromatography
By Henry Thomas, Stephanie Vine
November 19, 2025
Southwest Research Institute chemists share how a chance mishap with deionized water led to a method that may accelerate the purification of active drug ingredients
6 min read
What I Learned Bringing Slalom Chromatography Back from the Dead
By Fabrice Gritti
November 18, 2025
Fabrice Gritti spent a year immersed in the world of DNA physics to resurrect a long-abandoned technique to solve modern challenges in cell and gene therapy analysis
6 min read
Oligonucleotides: Synthesis and Manufacturing Hurdles
November 18, 2025
As oligonucleotides gain traction, manufacturing capabilities and analytical systems are being retooled to meet new demands for scale, purity, and efficiency.
4 min read
The Analytical Scientist Innovation Awards 2025: #4
By James Strachan
November 11, 2025
IonOpticks’ Aurora Series Capillary Flow Column Range combines proteomic depth with long-term stability – with insights from R&D scientists Andreia Almeida and Greta Briedyte
5 min read
The Analytical Scientist Innovation Awards 2025: #5
November 10, 2025
Introducing the Agilent 1290 Infinity III Hybrid Multisampler – Feed Injection technology for enhanced HPLC/UHPLC performance
2 min read
