Formic Acid Boosts LC-MS Metabolomics Sensitivity
November 20, 2025
A small tweak to sample prep – formic acid pretreatment – enhances LC–MS sensitivity and metabolome coverage without compromising reproducibility
2 min read
False
Liquid Chromatography
How Tap Water Sparked a Breakthrough in Ion-Assisted Chromatography
By Henry Thomas, Stephanie Vine
November 19, 2025
Southwest Research Institute chemists share how a chance mishap with deionized water led to a method that may accelerate the purification of active drug ingredients
6 min read
What I Learned Bringing Slalom Chromatography Back from the Dead
By Fabrice Gritti
November 18, 2025
Fabrice Gritti spent a year immersed in the world of DNA physics to resurrect a long-abandoned technique to solve modern challenges in cell and gene therapy analysis
6 min read
Oligonucleotides: Synthesis and Manufacturing Hurdles
November 18, 2025
As oligonucleotides gain traction, manufacturing capabilities and analytical systems are being retooled to meet new demands for scale, purity, and efficiency.
4 min read
The Analytical Scientist Innovation Awards 2025: #4
By James Strachan
November 11, 2025
IonOpticks’ Aurora Series Capillary Flow Column Range combines proteomic depth with long-term stability – with insights from R&D scientists Andreia Almeida and Greta Briedyte
5 min read
The Analytical Scientist Innovation Awards 2025: #5
November 10, 2025
Introducing the Agilent 1290 Infinity III Hybrid Multisampler – Feed Injection technology for enhanced HPLC/UHPLC performance
2 min read
Blood-Brain Barrier Stays Intact in Alzheimer’s Model
November 3, 2025
New findings suggest the brain’s defences hold steady in Alzheimer’s models, challenging assumptions on permeability
2 min read
Monodisperse Microspheres: No “Revolution” – But Excitingly Scalable
By Frantisek Svec
October 30, 2025
Bo Zhang’s new column technology itself isn’t “revolutionary,” argues Frantisek Svec, but he is excited about the potential for large-scale production
3 min read
Field Flow Fractionation Comes of Age
By Alina Astefanei
October 23, 2025
By preserving sample integrity, FFF meets modern separation challenges found at the intersection of the nano, micro, and macromolecular worlds
11 min read
Two-Minute PFAS Test
October 2, 2025
A new sensor device delivers real-time PFOS detection, combining machine learning with nanoscale graphene engineering
2 min read
