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Techniques & Tools Sample Preparation

Principles of Triple Detection GPC/SEC

| Sponsored by Malvern Panalytical

Triple detection GPC/SEC combines measurements from multiple detectors to offer not only increased amounts of data, but also increased amounts of information, which is made available by the combination of different detectors (and unobtainable using individual detectors separately). The theory of triple detection GPC/SEC is described here.

Techniques & Tools Sample Preparation

Using OMNISEC to Understand the Effect of Molecular Weight and Structure on the Performance Characteristics of Cellulose Derivatives

| Sponsored by Malvern Panalytical

This application note describes the analyses of a variety of aqueous (water-soluble) cellulose derivatives using the OMNISEC triple detection system and the subtle, yet distinct differences between these different derivatives that can be parsed out by the OMNISEC system

Techniques & Tools Sample Preparation

Characterizing polysaccharide structure with SEC-MALS and intrinsic viscosity measurements

| Sponsored by Malvern Panalytical

In this application note, molecular weight data from the Viscotek SEC-MALS 20 is combined with measurements of Rg and IV to study the structure of different polysaccharides including pullulan, dextran, hydroxypropyl cellulose (HPC), pectin and gum Arabic. The differences between conformation and Mark-Houwink plots are also studied.

Techniques & Tools Sample Preparation

Case study of a semi-pure β-amylase extract

| Sponsored by Malvern Panalytical

The investigative power of multiple detectors. Here, we describe the analysis of a semi-purified protein mixture containing β-amylase. Step-by-step, we show how different properties of the proteins elicit a specific response in each detector and how coupling this data can be qualitatively and quantitatively evaluated.

Fields & Applications Technology

Image of the Month

| Rich Whitworth

Benthoctopus sp gets overly familiar with Alvin’s robotic manipulator arm at 2,300 meters down in the Gulf of Mexico.

Fields & Applications Gas Chromatography

GC-MS and the Art of POP Analysis

| Esteban Abad Holgado

Persistent organic pollutants (POPs) encompass a wide variety of contaminants, but they share one thing in common: they have the potential to hit headlines and cause huge disruption to the food and feed industry.

Fields & Applications Spectroscopy

Small-footprint Absorbance System for Characterizing Heme Proteins

| Yvette Mattley

Compact Spark spectral sensor measures Vis-NIR absorbance of hemoglobin – and more

Techniques & Tools Technology

Dioxin Determination in Air Filter Samples Using Pressurized Solvent Extraction (PSE)

| Sponsored by Buchi

Extraction of air sampling filters for the determination of dioxins using BUCHI’s SpeedExtractor E-914

Techniques & Tools Mass Spectrometry

Screening, Identifying, and Quantifying Potential Genotoxic Compounds with High Resolution LC/MS

| Syed Salman Lateef

Analysis of chlorhexidine drug substance using an Agilent 6545 Accurate Mass Q-TOF System and MassHunter Mass Profiler Software.

Techniques & Tools Gas Chromatography

Applying the Basics

| Carlo Bicchi

Sitting Down With… Carlo Bicchi, Professor of Pharmaceutical Biology at the University of Turin, and member of the scientific committee for the 40th International Symposium on Capillary Chromatography and 13th GC×GC Symposium (Riva 2016), Italy.

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