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Fields & Applications Sample Preparation

The application of MicroCal VP Capillary DSC at a contract development organization

See how you can use DSC to save you money in your contract development lab. This paper provides an overview of the workflow typically associated with preformulation projects at a contract development organization as well as provides a general framework for conducting preformulation studies that leverages the application of biophysical techniques such as DSC and traditional analytics by employing statistical design. A case study involving the formulation development of a monoclonal antibody is presented to detail the utility and potential limitations of DSC in support of preformulation for a variety of protein products.

Techniques & Tools Data Analysis

LC-MS Versus GC-MS

| Rich Whitworth

Is the heat applied in gas chromatography-mass spectrometry really responsible for false results? And, if so, how often?

Techniques & Tools Gas Chromatography

The Power of Passionate Debate

| Rich Whitworth

Peer reviews, Power Lists and the effects of heat (in GC and discussions).

Techniques & Tools Liquid Chromatography

Tea With… Gérard Hopfgartner

| Gérard Hopfgartner

Tea With Rich returns with six 2015 Power Listers from HPLC in Geneva.

Fields & Applications Food, Beverage & Agriculture

Sensitive analysis of the lactose content of lactose-free labelled products using HPAEC-PAD

| Sponsored by Knauer

The market for lactose-free products is growing rapidly and constantly and Europe is a worldwide leader in the lactose-free market.

Techniques & Tools Mass Spectrometry

Trace LC-MS Analyses of Hormones in Potable Water and in Ultrapure Water

| Sponsored by Merck Millipore

Hormones are examples of contaminants of emerging concern (CEC) that have been detected in environmental and drinking waters around the world in trace amounts (1, 2).

Techniques & Tools Microscopy

Supercharging Correlative Microscopy

| Olaf Hollricher

Equipping scanning electron microscopes with Raman imaging to create a 2014 Innovation Award-winning universal microscopy solution.

Techniques & Tools Mass Spectrometry

A Taste of the Other Side

| Richard Fussell

When Richard Fussell still worked at the UK’s Food and Environment Research Agency, he was the first customer to see the Thermo Scientific Q Exactive™ GC in action – well ahead of its official launch at ASMS 2015. The latest Orbitrap™ innovation made him wonder – not for the first time – if the grass was greener on the other side.

Techniques & Tools Technology

Orbitrap™: Ten Years Young

| Alexander Makarov

Coupling gas chromatography with Orbitrap™ technology wasn’t easy, but the outcome – the introduction of the Thermo Scientific Q Exactive™ GC – represents a big step towards bringing full-scan, high-resolution, and accurate mass data into routine labs around the world. And my dream of an “Orbitrap in every lab” inches ever closer.

Fields & Applications Mass Spectrometry

Living in a Material World

| John Gilbert

Research into migration of packaging materials into food began decades ago. And despite the relatively inconspicuous nature of this niche area, it is characterized by some of the most significant modern-day challenges in food analysis.

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