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HPLC analysis of phosphopeptides using a bioinert column

This application note demonstrates the benefit of specifically designed column hardware for biomolecules, which contain phosphate group(s). This includes:

  • (Phospho-)peptides
  • Nucleotides
  • Oligonucleotides

The YMC Accura column hardware has been designed to eliminate any interaction between sample and stainless steel due to a strict coating of column body and frit. It allows sharp peaks, stable recoveries and eliminates consequential carry-over effects. This makes it a great choice for working at trace-levels.

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