YMC

The separation of very similar substances such as isomers has proved as challenging.

Cation exchange chromatography (CEX) is perceived to be the gold standard for the charge sensitive characterisation of monoclonal antibodies (MAbs).

Chlorophenols are used as pesticides, bleaching agents and disinfectants.

The DAR of the SigmaMAb ADC-mimic was determined using YMC’s BioPro HIC BF column and a nanospray ionisation MS.

In this application note, the separation of MAb samples and their oxidised species using YMC’s HIC column, BioPro HIC BF, is described.

Cation exchange chromatography is a non-denaturing technique used for separation & isolation of protein charge variants before characterisation via MS

Monoclonal antibodies (MAbs) are high-potency agents mainly used in cancer therapy or to combat auto-immune diseases

Cannabidiol is a non-psychoactive cannabinoid which has an easing, anti-inflammatory and antianxiety effect and is used to ease nausea.

Cation exchange chromatography (CEX) is perceived to be the gold standard for the charge sensitive characterisation of monoclonal antibodies (MAbs).

Drug-to-antibody ratios of antibody-drug-conjugates such as brentuximab vedotin is important for their therapeutic efficacy and pharmacokinetics.