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Genomics & DNA Analysis

Fields & Applications Mass Spectrometry

Dried Blood Spot 101

| Sangeeta Tanna, Graham Lawson

Introduced by Robert Guthrie in the 1960s, dried blood spot (DBS) sampling involves taking small drops ... of blood from either a finger prick (or heel prick in neonates) and depositing them on specially manufactured absorbent card where they are allowed to dry. Once dry, DBS cards can be readily transported by post for analysis since the components of the blood remain unchanged for several days, even at room temperature. For analysis, a portion of the blood spot is removed from the card and placed in a solvent to extract the analyte(s) of interest.

Fields & Applications Mass Spectrometry

Spot On

| Sangeeta Tanna, Graham Lawson

Dried Blood Spot (DBS) sampling is being adopted in drug development, paediatric healthcare, and, more recently, patient compliance.

Techniques & Tools Technology

Digital Versatile DNA

| Rich Whitworth

Can deoxyribonucleic acid solve our spiralling digital data archive conundrum? Hard disc drive space is now ... measured in terabytes not megabytes. And yet still we run out of space – or money.

Fields & Applications Genomics & DNA Analysis

DNA Horse Play

| Rich Whitworth

The horsemeat scandal has damaged customer confidence and raised food analysis awareness.

Fields & Applications Genomics & DNA Analysis

Science Dating

| Rich Whitworth

Need to conduct an experiment but lack technical capability?

Fields & Applications Genomics & DNA Analysis

Winter of Content

| Rich Whitworth

The remains of King Richard III are confirmed by DNA analysis, supported by micro-computed X-ray tomography and radiocarbon dating.

Fields & Applications Clinical

A Template for Citizen Science?

| Rich Whitworth

At the end of 2012, uBiome launched the world’s first crowdsourced research on the human microbiome.

Fields & Applications Microscopy

LC-MS/MS Method for the Determination of Diclofenac in Human Plasma

| Sponsored by Thermo Fisher Scientific

A liquid chromatography-tandem mass spectrometry method for the determination of diclofenac in human plasma was developed...

Fields & Applications Genomics & DNA Analysis

MicroRNA Detection

| Rich Whitworth

Chemistry researcher Tom Vosch and plant molecular biologist Seong Wook Yang have designed a …

Fields & Applications Genomics & DNA Analysis

The Tools Behind Genomics

| Norm Dovichi, Amanda Hummon

What underpinned three decades of explosive growth in genomics?

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