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Techniques & Tools Sample Preparation

GPC/SEC analysis of polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA) using OMNISEC

| Sponsored by Malvern Panalytical

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

Techniques & Tools Mass Spectrometry

Chromatography: Winning Every Battle, Losing the War?

| Hans-Gerd Janssen

Other techniques are beating chromatography and mass spectrometry to the hero’s reward all too often. Are they better? No. Are they faster to first result? Yes. Is it time to acknowledge that – on the frontlines – fit-for-purpose triumphs over best-in-class? You decide.

Techniques & Tools Liquid Chromatography

Gurus of Chiral Separations

| Christopher J. Welch, Yoshio Okamoto, Bernard Testa, Wolfgang Lindner

In Lewis Carroll’s 1871 novel, Through the Looking-Glass, Alice suggests to her black kitten, “Perhaps Looking-Glass milk isn’t good to drink...” And though our four gurus don’t attempt to predict the potability of milk from a mirror world, they keenly address the broader significance of chirality, the major milestones in chiral analysis, and where the field is heading.

Techniques & Tools Liquid Chromatography

Free Spirit

| Purnendu Dasgupta

Jenkins Garrett Professor of Chemistry and Biochemistry, University of Texas at Arlington, USA.

Techniques & Tools Mass Spectrometry

Ultrasensitive Detection of Mercury: Beyond FRET

| Sponsored by Ocean Optics

Rapid screening for total mercury content of water, soils and fish takes to the field

Techniques & Tools Pharma & Biopharma

Electrifying Analysis in R&D

| Mark R. Taylor, Susana Da Silva Torres

Electrochemical reaction cells are finding new applications in the pharma R&D lab that could offer big time and cost savings. Here, we share our experiences using electrochemistry with on-line mass spectrometry to study pharmaceutical stability and oxidation products – and explain why we’re electrochemistry converts.

Techniques & Tools Forensics

Adding Science Behind the Canine

| John DeHaan, Gareth S. Dobson, David Matthew

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Techniques & Tools Technology

Computer-aided Chromatography

| Eva Tyteca

We need to extend the limits of gradient condition optimization beyond reversed-phase separations.

Techniques & Tools Data Analysis

Making Room for Improvement

| Dennis Åsberg

To make way for more flexible approved analytical methods, we need a better understanding of the underlying scientific principles.

Techniques & Tools Liquid Chromatography

Fishing with Ion Chromatography Suppressors

| Purnendu Dasgupta

Combining knowledge from multiple fields inspired a solution to a problem in ion chromatography. What a shame the manufacturer didn’t take the bait...

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