Cookies

Like most websites The Analytical Scientist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Techniques & Tools Pharma & Biopharma, Technology

Fast and Furious – a Modern Way of assessing ADCC Activity

sponsored by Tosoh

View on demand

May 29, 2019 - 3pm BST / 4pm CEST / 10am EDT


Fc receptor affinity chromatography separates IgG glycoforms based on their ADCC activity.

A revolutionary HPLC column makes use of the FcγIIIa receptor, which plays a key role in antibody-dependent cell-mediated cytotoxicity (ADCC) by interacting with the Fc domain of immunoglobulins.

This rapid analysis can be applied to purified samples and supernatant alike and can be used in many phases of development and production such as cell line screening, upstream optimization, glycoengineering, biosimilar/originator comparison or lot comparison.

This webinar will give an introduction to the principle of FcR affinity chromatography, the influence of Fc-glycans on the separation profile and potential applications.

Learning Objectives of Webinar

  1. Discover a ground-breaking tool for fast ADCC activity assessment.
  2. Learn what FcR receptor affinity tells us about mAb glycoforms.
  3. Find out how antibody research, development, and production can benefit.

View on demand

Enjoy our FREE content!

Log in or register to gain full unlimited access to all content on the The Analytical Scientist site. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

Newsletter

Send me the latest from The Analytical Scientist.

Sign up now

Most Popular

Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine

Register