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Application Notes by Tosoh

Expanding the Boundaries of Light Scattering Detection

| Contributed by Tosoh

Light scattering detection (LS) is a widely used technique to obtain the “absolute” or true molecular weight of macromolecules.

Molecular Weight Determination of VLPs Using LENS3 Multi-Angle Light Scattering Detector

| Contributed by Tosoh

Viruses and virus like particles (VLPs) are multimeric protein structures that mimic native viruses but are non-infectious.

A New Paradigm in Light Scattering Technology

| Contributed by Tosoh

A Revolutionary Technology for Macromolecular Characterization.

How Fc receptor affinity chromatography correlates with antibody glycosylation and ADCC

| Contributed by Tosoh

Antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of action (MoA) of monoclonal antibodies used in cancer treatment.

FCR Affinity Chromatography - A New Approach to Assess Glycan Profiles During Cell Line Screening and Upstream Development

| Contributed by Tosoh

Fc-glycans of therapeutic antibodies are known to play an important role in the recognition of antibodies by the FcγIIIa receptor.

Characterization of Recombinant Protein Biotherapeutics by UHPLC-SEC-MALS

| Contributed by Tosoh

Biotherapeutics are generally larger molecules such as peptides, proteins and monoclonal antibodies

Analysis of Large Immunoglobulins by UHPSEC

| Contributed by Tosoh

Today new antibody formats are entering clinical phases some of which are larger than conventional mAbs

HPLC Column for quick Evaluation of ADCC Activity

| Contributed by Tosoh

Tosoh Bioscience introduced TSKgel FcR-IIIA-NPR a new HPLC affinity column based on recombinant FcγIIIa receptor, a key player in ADCC.

Analysis of Therapeutic Oligonucleotides by UHPSEC-MALS

| Contributed by Tosoh

The oligonucleotide therapeutics field has seen remarkable progress over the last few years and oligonucleotides are increasingly recognized as...

Analysis of Therapeutic Oligonucleotides by SEC-MALS

| Contributed by Tosoh

Oligonucleotides are increasingly recognized as therapeutics.

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