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Food, Beverage & Agriculture

Techniques & Tools Sample Preparation

Characterizing polysaccharide structure with SEC-MALS and intrinsic viscosity measurements

| Sponsored by Malvern Panalytical

In this application note, molecular weight data from the Viscotek SEC-MALS 20 is combined with measurements of Rg and IV to study the structure of different polysaccharides including pullulan, dextran, hydroxypropyl cellulose (HPC), pectin and gum Arabic. The differences between conformation and Mark-Houwink plots are also studied.

Techniques & Tools Sample Preparation

Case study of a semi-pure β-amylase extract

| Sponsored by Malvern Panalytical

The investigative power of multiple detectors. Here, we describe the analysis of a semi-purified protein mixture containing β-amylase. Step-by-step, we show how different properties of the proteins elicit a specific response in each detector and how coupling this data can be qualitatively and quantitatively evaluated.

Fields & Applications Technology

Absolute molecular weight’s measurements of synthetic polymers using the Viscotek SEC-MALS 20

The molecular weight, molecular weight distribution and size of two common polymers are measured using SEC-MALS 20. Results from SEC-MALS and conventional calibration are compared and discussed.

Fields & Applications Spectroscopy

Analysis of different of PLA/PLGA polymer samples using a GPC/SEC system

Usually, PLA and PLGA are based on monomers from renewable sources, so are considered “green” polymers. By selecting different molecular weights, different ratios of lactic:glycolic acid and different molecular structures, some properties such as degradation or drug release rates can be tailored to meet application needs. GPC/SEC analysis is an ideal tool for monitoring samples during material synthesis, production of parts and in degradation studies.

Fields & Applications Mass Spectrometry

Raising the Bar for Routine Analysis

| Sponsored by Thermo Fisher Scientific

The Pesticide Explorer Collection comprises four complete workflows that meet the challenges of modern pesticide residue analysis.

Fields & Applications Mass Spectrometry

Protecting Our Most Precious Resource: Water

| Heinz Singer

New analytical capability can have a significant impact on research direction.

Fields & Applications Spectroscopy

Using OMNISEC Triple-Detection GPC to Determine Structure of Dextrans and Other Polysaccharides

This application note will describe the analysis of a series of dextran samples ranging in molecular weight from about 1 – 650 kDa. Structural comparisons to other polysaccharides, gum arabic and pectin are presented. Initially discovered by Louis Pasteur in 1861, dextran is a polysaccharide that has found a variety of applications, primarily in the medical field, due to its minimal side-effects and solubility in aqueous media.

Fields & Applications Mass Spectrometry

The Never-Ending Challenge of Pesticide Analysis

| Rich Whitworth

A growing target list, increasingly complex matrices, and the need for low limits of detection can make our field seem like an uphill treadmill.

Fields & Applications Sample Preparation

Evaluating the rheological properties of hyaluronic acid hydrogels for dermal filler applications

To formulate successfully with HA it is essential to understand the impact of factors such as molecular weight, molecular structure, concentration and degree of cross-linking on rheological characteristics such as viscoelasticity which are directly linked to aspects of product performance. Linking structural characteristics to product performance, via rheological properties, supports smart, fast, and effective formulation. The following study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.

Techniques & Tools Food, Beverage & Agriculture

Hot (Dog) or Hype?

| Rich Whitworth

Kickstarter technology is nothing new – but Clear Labs is making in-roads into something less common: kickstarter analytical science

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