The Analytical Scientist Power List returns to celebrate the successes of the field’s leading lights!
02/18/2016 | Sponsored by Malvern Panalytical
In this application note, molecular weight data from the Viscotek SEC-MALS 20 is combined with measurements of Rg and IV to study the structure of different polysaccharides including pullulan, dextran, hydroxypropyl cellulose (HPC), pectin and gum Arabic. The differences between conformation and Mark-Houwink plots are also studied.
The investigative power of multiple detectors. Here, we describe the analysis of a semi-purified protein mixture containing β-amylase. Step-by-step, we show how different properties of the proteins elicit a specific response in each detector and how coupling this data can be qualitatively and quantitatively evaluated.
12/11/2015
The molecular weight, molecular weight distribution and size of two common polymers are measured using SEC-MALS 20. Results from SEC-MALS and conventional calibration are compared and discussed.
Usually, PLA and PLGA are based on monomers from renewable sources, so are considered “green” polymers. By selecting different molecular weights, different ratios of lactic:glycolic acid and different molecular structures, some properties such as degradation or drug release rates can be tailored to meet application needs. GPC/SEC analysis is an ideal tool for monitoring samples during material synthesis, production of parts and in degradation studies.
12/10/2015 | Sponsored by Thermo Fisher Scientific
The Pesticide Explorer Collection comprises four complete workflows that meet the challenges of modern pesticide residue analysis.
12/10/2015 | Heinz Singer
New analytical capability can have a significant impact on research direction.
12/09/2015
This application note will describe the analysis of a series of dextran samples ranging in molecular weight from about 1 – 650 kDa. Structural comparisons to other polysaccharides, gum arabic and pectin are presented. Initially discovered by Louis Pasteur in 1861, dextran is a polysaccharide that has found a variety of applications, primarily in the medical field, due to its minimal side-effects and solubility in aqueous media.
11/17/2015 | Rich Whitworth
A growing target list, increasingly complex matrices, and the need for low limits of detection can make our field seem like an uphill treadmill.
11/16/2015
To formulate successfully with HA it is essential to understand the impact of factors such as molecular weight, molecular structure, concentration and degree of cross-linking on rheological characteristics such as viscoelasticity which are directly linked to aspects of product performance. Linking structural characteristics to product performance, via rheological properties, supports smart, fast, and effective formulation. The following study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.
11/16/2015 | Rich Whitworth
Kickstarter technology is nothing new – but Clear Labs is making in-roads into something less common: kickstarter analytical science
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On an IM-MS Crusade
Lighting Up Archaeological Science
The Winner Takes It All