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Forensics

Fields & Applications Sample Preparation

Polyol-induced increases in thermal stability of antibodies by DSC

Polyol-induced increases in thermal stability of antibodies. See how Differential scanning calorimetry can be used to assess the effects of polyol excipients on antibodies. DSC was used to monitor polyol-induced increases in thermal stability across seven monoclonal antibodies. The increases in thermal stability were measured as a function of polyol concentration and orientation of hydroxyl groups. It was found that increases in thermal stability were linear with respect to alcohol concentration.

Fields & Applications Forensics

Quis Custodiet Ipsos Custodes

| Clifford Spiegelman, William Tobin

Conducting an autopsy of the flaws of comparative bullet lead analysis in forensic practice

Fields & Applications Sample Preparation

Microcalorimetry as a tool for structural biology

Learn how Isothermal titration calorimetry can be used to guide protein (RNA)/ligand crystallization and to resolve common issues with crystallization of complexes.

Fields & Applications Sample Preparation

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Fields & Applications Spectroscopy

Spectroscopy brought down to size

| Heinz Siesler

New developments are mobilizing Raman, mid-infrared and near-infrared spectroscopy for a whole host of innovative handheld applications.

Fields & Applications Sample Preparation

Ten reasons protein characterization scientists should upgrade from single to multi-detector SEC

The top 10 reasons to consider an advanced multi-detector SEC system, which incorporates light scattering detectors for the measurement of absolute molecular weight and molecular weight distribution with excellent accuracy.

Fields & Applications Forensics

Forensic Science Under Fire

| Jose Almirall

Hair analysis has been spectacularly debunked as “pseudoscience” – what now?

Techniques & Tools Forensics

Adding Science Behind the Canine

| John DeHaan, Gareth S. Dobson, David Matthew

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Fields & Applications Forensics

CSI: Dust DNA

| Bob Blackledge

Will the future see crime scene investigators collecting nasal swabs or rinses from deceased victims to identify the assailant? In a word: yes.

Techniques & Tools Liquid Chromatography

Cutting ACROSS Separation Science

| Paul Haddad

I’ve been running analytical chemistry research groups with military precision for decades. Over that time, I’ve had the good fortune to work with the brightest minds in the field on the most rewarding and exciting projects.

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