Materials

Manufacturing is getting smarter; only a cross-discipline approach will ensure the success of tomorrow’s processes.

Markes International connects with the local community – and gets the wider community to connect with analytical science.

This paper shows how using a solvent trap can be used to prevent sample drying/solvent loss during extended testing, helping to ensure that only rheological changes are being measured and not artifacts resulting from drying of the sample at the air/sample interface.

The top 10 reasons to consider an advanced multi-detector SEC system, which incorporates light scattering detectors for the measurement of absolute molecular weight and molecular weight distribution with excellent accuracy.

The stability of a protein sample and its tendency to aggregate is explored using a combination of SEC-MALS and DLS

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

In this white paper we examine the deformulation workflow, demonstrating the value of the technique of Morphologically Directed Raman Spectroscopy (MDRS) within this context. Case studies illustrate the relevance of MDRS data.

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.

Nearly half a century ago, J. Calvin Giddings published a letter that laid out his ideas for a new separation strategy. It resulted in a collection of techniques known as field-flow fractionation (FFF)

Even as advances in engineering technologies and manufacturing processes have lowered the cost to make and distribute products, the demand for continued improvement is as strong as ever.