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Fields & Applications

Fields & Applications Technology

Graduating from the Physical to the Chemical

| Joshua Windmiller

Why analytical chemistry must be leveraged in the next generation of wearable devices.

Fields & Applications Clinical

The 100,000 Genomes Project

| Stephanie Vine

An ambitious UK sequencing project aims to learn more about patients with cancer and rare diseases

Fields & Applications Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part 1)

A concern raised by the rise in routine MRI screening within the healthcare industry is that the ability to detect abnormalities within the body may currently be running ahead of our understanding of their possible consequences, making it difficult to determine a sound course of action. Here then analytical science is arguably advancing beyond current requirements.

Fields & Applications Food, Beverage & Agriculture

Sniffing Out Chirality

| Stephanie Vine

Odorant binding proteins could help to unlock new biosensors

Fields & Applications Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part 2)

In this second article of a short series Dr Paul Kippax is looking at the how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of multiple detectors to a GPC/SEC analysis…

Fields & Applications Data Analysis

DNA Imaging On-the-Go

| Stephanie Vine

Turn your smartphone into a portable fluorescence microscope for imaging and sizing DNA molecules

Fields & Applications

Classic Chemistry

| Rich Whitworth

Combining art and science is becoming a bit of a theme for The Analytical Scientist. Lewis Carroll’s reference to stereoisomers sent me down my own rabbit hole of discovery.

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Fields & Applications Mass Spectrometry

When Great Minds Think Alike

| Rich Whitworth

The M908 took the top spot in our 2013 Innovation Awards – “Revolutionary technology; will be an inspiration for new generations,” said the judges. Here, four co-founders of 908 Devices describe the perfect storm that led to the creation of the world’s first handheld mass spectrometer.

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