Fields & Applications

This application note presents an example of how calorimetry aided the formulation development for ProX by providing insight into excipient-protein interactions. Polysorbate-80 and phenol are examined here as potential additives to the formulation buffer for ProX.

The study of exosomes and other cell-derived microvesicles is an area of rapidly rowing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This document shows the degree to which the technique of Nanoparticle Tracking Analysis (NTA) is helping to address these problems.

Analytical QbD (AQbD) promises to extend the rigor and benefits of QbD into the area of analytical method development.

This month’s focus – The Art of Analysis – also highlights the power of ‘self marketing’. What can we learn from the USA and the younger generation?

Ole Gron has been in the pharmaceutical industry for over 10 years after finding his way into separation science via spectroscopy.

Concluding our series on two-dimensional liquid chromatography, we talk with a pair of relative newcomers who relate their experiences to date and discuss how they plan to take advantage of the technique in the future.

“Simulation” and biting aside, does the total lack of substance abuse mean that the beautiful game is clean?

New components and measurement techniques continue to be introduced for the Zetasizer Nano. New to the system are a Surface Zeta Potential accessory and a new diffusion barrier method for improved zeta potential measurements of protein samples. Why is the Malvern Zetasizer Nano so popular and found in a broad range of applied and fundamental scientifi c projects across all industries and fields? Because, it is simply the most dynamic and broad ranged instrument on the market for solving technical issues in today’s research environment and it continues to evolve with new capabilities. Here are 10 reasons why you should choose the Zetasizer Nano:

The Zetasizer NanoSampler is a sample delivery system that ensures highly precise and reproducible automated loading of samples into your Zetasizer Nano for particle size measurements. The NanoSampler adds automation and unattended operation in a versatile, compact package, maximising the productivity of your Zetasizer Nano.

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.