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Fields & Applications

Fields & Applications Sample Preparation

Differentiation and characterization of subvisible particulates in therapeutic protein products

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Fields & Applications Pharma & Biopharma

Harnessing 2D-LC for Big Pharma

| Cadapakam J. Venkatramani

Over 10 years ago, the potential of two-dimensional liquid chromatography seemed obvious to me – so I built a system and never looked back.

Fields & Applications Data Analysis

Targeting the Untargeted

| John A. McLean

Our capacity to generate data is unsurpassed, but how do we cope with the data deluge? It’s time to embrace data-driven discovery in biology and medicine.

Fields & Applications

Cartoon

| Nick Kim

Nick Kim gifts us with his very analytical and amusing view of the world around us.

Fields & Applications Food, Beverage & Agriculture

Micro GC Robots for Farmers

| Stephanie Vine

Taking gas chromatography into the field has the potential to detect crop disease sooner

Fields & Applications Clinical

Crafty Diagnostics

| Rich Whitworth

Could a simple flower-shaped paper-based assay be the answer to an undiagnosed hepatitis C pandemic?

Fields & Applications Proteomics

Parallel Proteomes

| Stephanie Vine

While Bernard Kuster and his colleagues were compiling ProteomicsDB, a separate team of researchers at Johns Hopkins University, Baltimore, USA, and the Institute of Bioinformatics, Bangalore, India, tackled the challenge in a different way

Fields & Applications Sample Preparation

Overcoming the negative effect of protein structure on molecular weight measurement by Size Exclusion Chromatography

In this application note we will look at two examples where the retention volume of a sample could not be used to obtain an accurate measure of the sample MW. We will also describe the additional information that can be obtained using these advanced detectors. This work has been performed in conjunction with the Institut Pasteur, Paris, France

Fields & Applications Food, Beverage & Agriculture

Tea With… Chiara Cordero

| Rich Whitworth

For our second episode, we stay in Italy and speak with Chiara Cordero from the University of Turin

Fields & Applications Data Analysis

Protein analysis with the Zetasizer MicroV batch & flow mode

The Zetasizer µV (MicroV) is a dual purpose light scattering instrument designed specifically for the analysis of proteins. Firstly, it is a highly sensitive cuvette based dynamic light scattering instrument with the same great performance as the market leading Zetasizer Nano. Secondly, by simply changing the cell, it becomes an absolute molecular weight and size detector that can be added to any Size Exclusion Chromatography system (such as the Viscotek TDAmax).

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