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Native AEX-MS analysis of IgG4-based mAbs

| Contributed by YMC

This note describes how the charge heterogeneity of IgG4-based mAbs with a pI between 6.1 to 7.3 (proprietary mAbs) can be successfully evaluated.

Business & Education Professional Development

What It Takes to Innovate

| Pieter Dorrestein | 3 min read

When expertise and interests align, collaboration breeds innovation

HRIM Revolutionizes PFAS Forensic Testing: Unveil Isomers & Boost ID Accuracy

| Contributed by MOBILion Systems Inc

Ion mobility reveals "dark matter" PFAS, undetected by standard tests, enhancing understanding and guiding mitigation.

Redefine the boundaries of spectral measurement!

| Contributed by Hamamatsu

A spectrometer measuring very weak and strong signals simultaneously in one device. The OPAL-Luxe has an unprecedented dynamic range of 2.5 Mio to 1.

Techniques & Tools Liquid Chromatography

What’s New in Chromatography?

| Markella Loi | 2 min read

The latest chromatography research – from moth aphrodisiacs to vaccine biomanufacturing

Fields & Applications Food, Beverage & Agriculture

Improving Cannabis Quality – from Seed to Sale

| Zacariah Hildenbrand

Cannabis analysis may have grown in sophistication in recent years, but several remaining challenges stand in the way of consistent QC

Techniques & Tools Mass Spectrometry

Fly Me to the Moon(s)

| Jessica Allerton | 3 min read

Putting analytical science to the ultimate test: looking for extraterrestrial life on moons within our solar system

Discover how Bristol-Myers Squibb uses electron-activated dissociation (EAD) to confidently identify drug metabolites and localize site of metabolism.

| Sponsored by SCIEX

In this study, the application of EAD in drug metabolite profiling is explored. The efficiency in the structural elucidation of conjugation metabolites is compared with that of CID.

Business & Education Business

Business in Brief

| Markella Loi | 2 min read

A roundup of this month’s business news – from partnerships to product launches, including a new in-line spectrometer for bioprocess control

Peptide Mapping of Adeno-Associated Virus Capsid Proteins

| Contributed by Phenomenex

The use of Adeno-Associated Viruses (AAV) as an effective vector for the delivery of ssDNA in gene therapy, is well established and continues to grow.

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