Liquid Chromatography

As new technology platforms push us to the limits of what’s possible, the metabolomics community is closing in on the future of the field: routine and rapid quantitative analysis.

Way back in the mid-1960s, somewhere in the North American Midwest, J. Calvin Giddings spent a sleepless night in a noisy motel room. Even the room’s rattling air-conditioning unit gave him a hard time.

Christoph Johann, founder and MD of Wyatt Technology Europe, the company that originally introduced field-flow fractionation (FFF) instrumentation to Europe’s analytical scientists, looks at the history of the technique and shares his involvement with the field.

For most of my industrial career, I’ve been a modeler and have had to deliver practical results.

The quest for greater separation power, in terms of peak capacity, has inevitably led to the development of multidimensional chromatographic techniques.

Ahead of ISCC & GC×GC 2015 symposium, we bring together a posse of multidimensional ranchers for a glimpse of what’s going on in the field – and what to expect at the Texan conference.

For years, thin layer chromatography has been working hard in the background, the choice technique in certain applications. More recently, hyphenation with mass spectrometry has been a relatively quiet – but very real – game-changer. What have you been missing?

Sitting Down With... Gérard Hopfgartner, Professor in Analytical Sciences and Mass Spectrometry and Head of the Mass Spectrometry Platform of the Sciences Faculty, University of Geneva, Switzerland.

When I was asked to evaluate a brand-new instrument with disruptive potential in my field, I did not spend long thinking about the answer. Here, I share a little background and my first impressions.

Supercritical fluid chromatography started out as anything but green. The road has been bumpy, but the modern technique cannot be ignored from an environmental perspective – despite its slight identity crisis.