Principles of Charged Aerosol Detector Method Development – from Simple Isocratic to Complex 2D Chromatographic Approaches.
Best practices for efficient method development for routine use of CAD are outlined in the first part of this webinar.
sponsored by Thermo Fisher Scientific
The Charged Aerosol Detector (CAD) and related techniques (e.g., evaporative light scattering detectors) have a nearly identical detection scope and the same eluent requirements. However, key differences in the downstream aerosol measurement technique, result in differences in the shape of the response curves, peak shape, sensitivity limits, and uniformity of response. The Thermo Scientific™ Charged Aerosol Detectors deliver flexibility, performance and ease-of-use for all labs to advance your work, where other systems fail to perform.
Best practices for efficient method development for routine use of CAD are outlined in the first part of this webinar.
In the second part, the development of two 2D-LC approaches using CAD and MS are described in detail for determining the heterogeneity and stability of polysorbates in MAb products.
Learning Objectives of Webinar
- Understanding charged aerosol detection.
- Optimizing method development for CAD.
- Making complex analytical approaches practical.
