Utilizing HFX-style NMR Experiments to Assist in Structure Elucidation of Fluorinated Small Molecules
sponsored by Jeol
Fluorinated molecules have continued to become more and more prominent in pharmaceutical, agricultural, and material science applications. Historically, NMR probes and techniques have been mainly focused on acquiring the spectra of hydrogen and carbon. Fluorine's NMR properties provide the chemist both additional tools as well as additional challenges in regards to complete structure elucidation.
This webinar will explore the way NMR probes have evolved over time, showcase a recent breakthrough in probe technology, and discuss additional experimental methods that have the potential to be useful to anyone who is trying to use NMR to confirm structures where fluorine is present.
Learning Objectives:
- Overview of NMR techniques relevant to small molecule structure elucidation
- Complexity in NMR spectra arising from the presence of fluorine atoms
- How HFX experiments can aid in assigning spectra by reducing complexity or enabling additional data to be acquired
