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Fields & Applications Sample Preparation

Differentiation and characterization of subvisible particulates in therapeutic protein products

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Fields & Applications Pharma & Biopharma

Harnessing 2D-LC for Big Pharma

| Cadapakam J. Venkatramani

Over 10 years ago, the potential of two-dimensional liquid chromatography seemed obvious to me – so I built a system and never looked back.

Techniques & Tools

Overcoming Your Resistance to Change

| Janice Manzi Sabatine

Is your “psychological immune system” preventing you from moving in positive new directions? By facing the hidden commitments that you harbor and challenging the assumptions that they are based upon, you really can modify your behavior. Here’s how.

Techniques & Tools Petrochem

The Power of Fully Integrated Informatics

| Colin Thurston, Ajith Kumar

Shell’s Pearl GTL brings in the big guns to tackle its vast data-handling requirements with an integrated laboratory information management system.

Techniques & Tools Pharma & Biopharma

Analytical Asset Management

| Ben Potenza

The promise of cash generated from idle and surplus equipment sounds great. But how can you turn theoretical gains into practical benefits?

Fields & Applications Data Analysis

Targeting the Untargeted

| John A. McLean

Our capacity to generate data is unsurpassed, but how do we cope with the data deluge? It’s time to embrace data-driven discovery in biology and medicine.

Techniques & Tools Gas Chromatography

Tea With… James Harynuk

| Rich Whitworth

Are mass spectral search libraries like crooked politicians? James Harynuk applies thermodynamic common sense to find the answer.

Techniques & Tools Technology

Command the Box

| Bill Anderson

Surely, we’ve gone beyond thinking outside the box – the time has come to tell the box to respond to our thoughts.

Techniques & Tools Mass Spectrometry

Building Mass Spectrometry from the Inside

| Ian Jardine

The development of mass spectrometry is one of science’s great technology stories.

Techniques & Tools Liquid Chromatography

Achiral-Chiral Heart-Cutting 2D-LC Analysis of Chiral Pharmaceutical Substances

| Sponsored by Agilent Technologies

Impurity analysis with simultaneous determination of enantiomeric composition using the Agilent 1290 Infinity 2D-LC Solution

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