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App Notes

Results 421–430 of 1416

Characterization of Recombinant Protein Biotherapeutics by UHPLC-SEC-MALS

| Contributed by Tosoh

Biotherapeutics are generally larger molecules such as peptides, proteins and monoclonal antibodies

Incorporating CCS Values to Enable 4-Dimensional Annotation of Metabolic Features

| Contributed by Bruker

Reliable annotation of metabolites for LC-MS/MS based data requires the adept combination of many parameters.

Quantitative Analysis of Explosives by Thermal Desorption–GC–MS Method

| Contributed by CDS

This application note demonstrates quantitative analysis of explosive standards by thermally desorb the sample into a GC-MS

Multi-Step Pyrolysis of a Meteorite Using a Pyroprobe with GC/MS

| Contributed by CDS

In the search for extraterrestrial life, finding organic molecules has been a topic of special interest

Ion-Pair ReversedPhase Analysis of an Oligonucleotide Ladder Standard with Avantor® ACE® Oligo

| Contributed by Avantor

Oligonucleotides are short lengths of DNA/RNA which are being used as therapeutic agents for the treatment of genetic disorders and cancers

Evolved Gas Analysis and Multi-step Pyrolysis of Mascara Using the Pyroprobe with GC/MS

| Contributed by CDS

This application note demonstrates evolved gas analysis and multi-step pyrolysis on two different mascaras.

Analysis of commercial monoclonal antibodies by microLC-MS/MS

| Contributed by YMC

Monoclonal antibodies (MAbs) are high-potency agents mainly used in cancer therapy or to combat auto-immune diseases

Analysis of Large Immunoglobulins by UHPSEC

| Contributed by Tosoh

Today new antibody formats are entering clinical phases some of which are larger than conventional mAbs

Determination of Epoxy to Hardener Ratios in a Cycloaliphatic Epoxy

| Contributed by CDS

Epoxy resin is a type of synthetic resin that could be used in a wide range of applications

Bottom-up Proteomic Profiling Using μPAC™ CapLC Columns

| Contributed by Pharma Fluidics

Combining improved sensitivity with analytical flow robustness and throughput

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