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Clinical

Fields & Applications Sample Preparation

Microcalorimetry as a tool for structural biology

Learn how Isothermal titration calorimetry can be used to guide protein (RNA)/ligand crystallization and to resolve common issues with crystallization of complexes.

Fields & Applications Clinical

Simpler Blood Sampling

| Rich Whitworth

hemaPEN aims to rewrite the textbook for disease screening, therapeutic drug monitoring and medical research

Fields & Applications Sample Preparation

Laser diffraction and automated imaging: complementary techniques for nasal spray development

The techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance. This paper examines their application.

Techniques & Tools Clinical

Biosensing Gets Smart

| Stephanie Vine

Australian researchers harness the power of smartphone biosensing – without the need for specialized components

Techniques & Tools Mass Spectrometry

Holistic Bioanalytics

| Rich Whitworth

Lawrence (Larry) Lesko is a bioanalytical veteran with many years of academic and FDA experience. Now, as director of the University of Florida’s Center for Pharmacometrics and Systems Pharmacology, Larry uses metabolomics to discover biomarkers of drug toxicity.

Fields & Applications Sample Preparation

Protein stability measurements amplified: Combining SEC-MALS and DLS to maximize data output

The stability of a protein sample and its tendency to aggregate is explored using a combination of SEC-MALS and DLS

Techniques & Tools Pharma & Biopharma

Finding Humanity in Science

| Rich Whitworth

What drives someone to throw aside selfish pursuits to focus on projects with true philanthropic impact? Here, the winners of the 2015 Humanity in Science Award provide their answers.

Techniques & Tools Spectroscopy

Driving SERS into the Clinic

| Mustafa Culha

Raman spectroscopy has evolved into a powerful characterization technique for many applications. What more needs to be done to make it effective in clinical analysis?

Fields & Applications Sample Preparation

Measurements of absolute molecular weight of synthetic polymers

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

Fields & Applications Clinical

Skin Deep Biosensing

| Stephanie Vine

Simultaneous monitoring of multiple metabolites – with a chip beneath the surface of your skin

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