Pharma & Biopharma

Lawrence (Larry) Lesko is a bioanalytical veteran with many years of academic and FDA experience. Now, as director of the University of Florida’s Center for Pharmacometrics and Systems Pharmacology, Larry uses metabolomics to discover biomarkers of drug toxicity.

The stability of a protein sample and its tendency to aggregate is explored using a combination of SEC-MALS and DLS

Liquid chromatography is not just an analytical tool for today, it offers a great deal for the future.

We must inspire creative minds to keep LC moving forward

What drives someone to throw aside selfish pursuits to focus on projects with true philanthropic impact? Here, the winners of the 2015 Humanity in Science Award provide their answers.

Simultaneous monitoring of multiple metabolites – with a chip beneath the surface of your skin

Using NMR spectroscopy to investigate the structure of monoclonal antibodies

In the quest for increased sensitivity or higher resolution, let’s not lose sight of our objectives.

In this white paper we examine the deformulation workflow, demonstrating the value of the technique of Morphologically Directed Raman Spectroscopy (MDRS) within this context. Case studies illustrate the relevance of MDRS data.

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.