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Pharma & Biopharma

Fields & Applications Technology

Exosomes and Microvesicles: An introduction

The study of exosomes and other cell-derived microvesicles is an area of rapidly rowing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This document shows the degree to which the technique of Nanoparticle Tracking Analysis (NTA) is helping to address these problems.

Fields & Applications Sample Preparation

Beyond SOPs – Exploring the Rigor and Requirements of Analytical QbD

Analytical QbD (AQbD) promises to extend the rigor and benefits of QbD into the area of analytical method development.

Fields & Applications Pharma & Biopharma

The Impurity Analyst

| Rich Whitworth

Ole Gron has been in the pharmaceutical industry for over 10 years after finding his way into separation science via spectroscopy.

Fields & Applications Pharma & Biopharma

The New 2D-LC Kids on the Block

| Rich Whitworth

Concluding our series on two-dimensional liquid chromatography, we talk with a pair of relative newcomers who relate their experiences to date and discuss how they plan to take advantage of the technique in the future.

Techniques & Tools Pharma & Biopharma

The Bumpy Road from Chemist to Entrepreneur

| Elizabeth Thomas

Starting my own bioanalytical research company after many years working for Big Pharma has been daunting, but also satisfying, and I wouldn’t have missed it for the world.

Fields & Applications Sample Preparation

10 Reasons that the Zetasizer Nano is chosen for scientific success

New components and measurement techniques continue to be introduced for the Zetasizer Nano. New to the system are a Surface Zeta Potential accessory and a new diffusion barrier method for improved zeta potential measurements of protein samples. Why is the Malvern Zetasizer Nano so popular and found in a broad range of applied and fundamental scientifi c projects across all industries and fields? Because, it is simply the most dynamic and broad ranged instrument on the market for solving technical issues in today’s research environment and it continues to evolve with new capabilities. Here are 10 reasons why you should choose the Zetasizer Nano:

Fields & Applications Sample Preparation

Automated particle size with Zetasizer NanoSampler

The Zetasizer NanoSampler is a sample delivery system that ensures highly precise and reproducible automated loading of samples into your Zetasizer Nano for particle size measurements. The NanoSampler adds automation and unattended operation in a versatile, compact package, maximising the productivity of your Zetasizer Nano.

Fields & Applications Sample Preparation

Differentiation and characterization of subvisible particulates in therapeutic protein products

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Fields & Applications Pharma & Biopharma

Harnessing 2D-LC for Big Pharma

| Cadapakam J. Venkatramani

Over 10 years ago, the potential of two-dimensional liquid chromatography seemed obvious to me – so I built a system and never looked back.

Techniques & Tools Pharma & Biopharma

Analytical Asset Management

| Ben Potenza

The promise of cash generated from idle and surplus equipment sounds great. But how can you turn theoretical gains into practical benefits?

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