Sample Preparation

Let’s go back to the early 1990s when an important innovation was starting to cause a stir. Electrospray ionization (ESI) essentially allowed liquid chromatography (LC) and mass spectrometry (MS) to be combined much more easily as an analytical technique.

Wolfgang discusses the spirit of science, Salzburg and ISC2014 in the latest episode of Tea with Rich.

There are a lot of things to consider when seeking good results from gas chromatography. Success often comes from understanding precisely what goes on in the injection port.

A concern raised by the rise in routine MRI screening within the healthcare industry is that the ability to detect abnormalities within the body may currently be running ahead of our understanding of their possible consequences, making it difficult to determine a sound course of action. Here then analytical science is arguably advancing beyond current requirements.

In this second article of a short series Dr Paul Kippax is looking at the how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of multiple detectors to a GPC/SEC analysis…

In this short series of articles Dr Paul Kippax is looking at how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of Raman spectroscopy to automated imaging…

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Accurate measurement drives progress in science in immeasurable ways. Here, we celebrate a year’s worth of advances in The Analytical Scientist Innovation Awards 2014. What impact will these 15 TASIA winners have on your field?