Spectroscopy

In this short series of articles Dr Paul Kippax is looking at how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of Raman spectroscopy to automated imaging…

Raman spectroscopy identifies rickets in 400-year-old bones from the Mary Rose

Is analytical science poised to storm the theatre and steal the spotlight? Possibly not. But I do sense an increasingly central – and recognized – role, particularly in the clinic.

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

Other techniques are beating chromatography and mass spectrometry to the hero’s reward all too often. Are they better? No. Are they faster to first result? Yes. Is it time to acknowledge that – on the frontlines – fit-for-purpose triumphs over best-in-class? You decide.

In Lewis Carroll’s 1871 novel, Through the Looking-Glass, Alice suggests to her black kitten, “Perhaps Looking-Glass milk isn’t good to drink...” And though our four gurus don’t attempt to predict the potability of milk from a mirror world, they keenly address the broader significance of chirality, the major milestones in chiral analysis, and where the field is heading.

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Is it time to drop your NIR instrument in the pool?

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Sitting Down With Nicoló Omenetto, Research Professor in the Department of Chemistry at the University of Florida, USA.