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Techniques & Tools Mass Spectrometry

Holistic Bioanalytics

| Rich Whitworth

Lawrence (Larry) Lesko is a bioanalytical veteran with many years of academic and FDA experience. Now, as director of the University of Florida’s Center for Pharmacometrics and Systems Pharmacology, Larry uses metabolomics to discover biomarkers of drug toxicity.

Fields & Applications Sample Preparation

Overcoming solvent evaporation/drying during rheological testing on rotational rheometer

This paper shows how using a solvent trap can be used to prevent sample drying/solvent loss during extended testing, helping to ensure that only rheological changes are being measured and not artifacts resulting from drying of the sample at the air/sample interface.

Fields & Applications Sample Preparation

Ten reasons protein characterization scientists should upgrade from single to multi-detector SEC

The top 10 reasons to consider an advanced multi-detector SEC system, which incorporates light scattering detectors for the measurement of absolute molecular weight and molecular weight distribution with excellent accuracy.

Fields & Applications Sample Preparation

Protein stability measurements amplified: Combining SEC-MALS and DLS to maximize data output

The stability of a protein sample and its tendency to aggregate is explored using a combination of SEC-MALS and DLS

Fields & Applications Sample Preparation

Optimizing Small Volume of Block Co-Polymers Used for Enhanced Oil Recovery

Read how DLS-based optical microrheology can be used to determine the rheological behavior of polymer solutions and the impact of tracer particle chemistry on the measured microrheological response.

Techniques & Tools Liquid Chromatography

Marking Progress

| Monika Dittman, Fabrice Gritti

Monika Dittman (Agilent Technologies) and Fabrice Gritti (Waters) offer a manufacturer point of view on the practical limits of LC.

Fields & Applications Liquid Chromatography

Marching Ever Onward

| Gert Desmet

The evidence contradicts those who say liquid chromatography has fully matured.

Techniques & Tools Pharma & Biopharma

Finding Humanity in Science

| Rich Whitworth

What drives someone to throw aside selfish pursuits to focus on projects with true philanthropic impact? Here, the winners of the 2015 Humanity in Science Award provide their answers.

Techniques & Tools Gas Chromatography

Reinventing GC-MS

| Joshua Coon

At ASMS 2015, GC-Orbitrap™ technology was unleashed onto an expectant analytical community. Here’s the backstory.

Techniques & Tools Spectroscopy

Driving SERS into the Clinic

| Mustafa Culha

Raman spectroscopy has evolved into a powerful characterization technique for many applications. What more needs to be done to make it effective in clinical analysis?

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