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Techniques & Tools Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part3)

| Sponsored by Malvern Panalytical

In this short series of articles Dr Paul Kippax is looking at how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of Raman spectroscopy to automated imaging…

Techniques & Tools Sample Preparation

GPC/SEC analysis of polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA) using OMNISEC

| Sponsored by Malvern Panalytical

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

Techniques & Tools Forensics

Adding Science Behind the Canine

| John DeHaan, Gareth S. Dobson, David Matthew

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Techniques & Tools Technology

Computer-aided Chromatography

| Eva Tyteca

We need to extend the limits of gradient condition optimization beyond reversed-phase separations.

Techniques & Tools Genomics & DNA Analysis

Jurassic Park Parchment

| Stephanie Vine

DNA from ancient archive gives researchers a window into animals of the past

Techniques & Tools Spectroscopy

Swimming with Spectroscopy

| Stephanie Vine

Is it time to drop your NIR instrument in the pool?

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Fields & Applications Mass Spectrometry

When Great Minds Think Alike

| Rich Whitworth

The M908 took the top spot in our 2013 Innovation Awards – “Revolutionary technology; will be an inspiration for new generations,” said the judges. Here, four co-founders of 908 Devices describe the perfect storm that led to the creation of the world’s first handheld mass spectrometer.

Techniques & Tools Technology

Return of the TASIAs

| Rich Whitworth

Accurate measurement drives progress in science in immeasurable ways. Here, we celebrate a year’s worth of advances in The Analytical Scientist Innovation Awards 2014. What impact will these 15 TASIA winners have on your field?

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