Clinical

How can we harmonize lab testing and pathology consultations to prevent lab-related diagnostic errors?

Advances in genomics are thrilling, but a tumor is more than a bundle of genetic information.

This article explores how multiple detectors, particularly light scattering detectors, may be used for size-exclusion chromatography (SEC) in protein analysis. Using a light scattering detector as part of a multi-detector Size Exclusion Chromatography system provides the accurate molecular weight (MW) data needed to assess the activity, safety and clinical efficacy of therapeutic proteins.

Tom Metz, Integrative Omics Scientist and Metabolomics Technical Lead at Pacific Northwest National Laboratory (Washington State, USA), selects six papers that exemplify the power of multi-omics.

From hardcore peptide biochemist to translational scientist, it’s been an unconventional journey for Jennifer Van Eyk, Director of the Advanced Clinical Biosystems Research Institute at Cedars-Sinai Medical Center, Los Angeles. Here, Jenny tells us what she’s learnt along the way.

Cancer is incredibly complex, posing enormous challenges beyond the biological field. Taking a multi-omic approach can help us make sense of this diverse set of diseases – and, ultimately, allow us to better understand ourselves as human beings.

When it comes to microsampling for quantitative bioanalysis, the devil is certainly in the details. But we should learn from our mistakes – not retreat back into convention.

Near-infrared spectroscopy may allow non-invasive monitoring of premature babies

In this application note, a purified polyclonal antibody (IgG) is separated using Size Exclusion Chromatography (SEC) and characterized using the Viscotek SEC-MALS 20, allowing calculation of molecular weight and radius of gyration (Rg).

Can comprehensive two-dimensional gas chromatography breath analysis lead to better lung cancer diagnostics?