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Clinical

Techniques & Tools Pharma & Biopharma

Finding Humanity in Science

| Rich Whitworth

What drives someone to throw aside selfish pursuits to focus on projects with true philanthropic impact? Here, the winners of the 2015 Humanity in Science Award provide their answers.

Techniques & Tools Spectroscopy

Driving SERS into the Clinic

| Mustafa Culha

Raman spectroscopy has evolved into a powerful characterization technique for many applications. What more needs to be done to make it effective in clinical analysis?

Fields & Applications Sample Preparation

Measurements of absolute molecular weight of synthetic polymers

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

Fields & Applications Clinical

Skin Deep Biosensing

| Stephanie Vine

Simultaneous monitoring of multiple metabolites – with a chip beneath the surface of your skin

Fields & Applications Sample Preparation

Accelerating the deformulation workflow for oral solid dosage forms

In this white paper we examine the deformulation workflow, demonstrating the value of the technique of Morphologically Directed Raman Spectroscopy (MDRS) within this context. Case studies illustrate the relevance of MDRS data.

Fields & Applications Sample Preparation

Detecting agglomerates within pharmaceutical formulations

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.

Fields & Applications Data Analysis

How to KISS (Keep it Simple, Stupid)

| Scott Phillips

Consider designing the readout first when developing point-of-need assays.

Fields & Applications Sample Preparation

Characterizing Opthalmic Viscosurgical Devices (OVDs) using a rotational rheometer

This application note discusses the methodology and results for the rheological characterization of Opthalmic Viscosurgical Devices (OVDs) according to the International Standard ISO15798:2013

Fields & Applications Mass Spectrometry

The Surgeon’s Perspective

| Steven Olde Damink

The primary value of M4I really lies in the investment in human capital (rather than simply MSI hardware)

Fields & Applications Mass Spectrometry

MultiModal Molecular Imaging

| Ron M. A. Heeren

Molecular imaging based on mass spectrometry provides a broad scope of analytical, molecular and local information that can be employed for patient phenotyping.

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