Pharma & Biopharma

Analytical QbD (AQbD) promises to extend the rigor and benefits of QbD into the area of analytical method development.

Ole Gron has been in the pharmaceutical industry for over 10 years after finding his way into separation science via spectroscopy.

Concluding our series on two-dimensional liquid chromatography, we talk with a pair of relative newcomers who relate their experiences to date and discuss how they plan to take advantage of the technique in the future.

Starting my own bioanalytical research company after many years working for Big Pharma has been daunting, but also satisfying, and I wouldn’t have missed it for the world.

New components and measurement techniques continue to be introduced for the Zetasizer Nano. New to the system are a Surface Zeta Potential accessory and a new diffusion barrier method for improved zeta potential measurements of protein samples. Why is the Malvern Zetasizer Nano so popular and found in a broad range of applied and fundamental scientifi c projects across all industries and fields? Because, it is simply the most dynamic and broad ranged instrument on the market for solving technical issues in today’s research environment and it continues to evolve with new capabilities. Here are 10 reasons why you should choose the Zetasizer Nano:

The Zetasizer NanoSampler is a sample delivery system that ensures highly precise and reproducible automated loading of samples into your Zetasizer Nano for particle size measurements. The NanoSampler adds automation and unattended operation in a versatile, compact package, maximising the productivity of your Zetasizer Nano.

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Over 10 years ago, the potential of two-dimensional liquid chromatography seemed obvious to me – so I built a system and never looked back.

The promise of cash generated from idle and surplus equipment sounds great. But how can you turn theoretical gains into practical benefits?

In this application note we will look at two examples where the retention volume of a sample could not be used to obtain an accurate measure of the sample MW. We will also describe the additional information that can be obtained using these advanced detectors. This work has been performed in conjunction with the Institut Pasteur, Paris, France