Mass Spectrometry

Monika Dittman (Agilent Technologies) and Fabrice Gritti (Waters) offer a manufacturer point of view on the practical limits of LC.

We must inspire creative minds to keep LC moving forward

At ASMS 2015, GC-Orbitrap™ technology was unleashed onto an expectant analytical community. Here’s the backstory.

Sitting Down With... Ruedi Aebersold, Deputy Head, Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Switzerland

Isotope dilution mass spectrometry analysis highlights effective interdisciplinary collaboration – and its legacy should be at the forefront of modern research.

How to bring better diagnostic tests to the market to benefit patients.

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

How to compare and contrast biosensor performance

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.

My love of biology, mass spectrometry and computer programming has led me down an uncommonly rewarding path of discovery and innovation. Here, I share some of my story and look towards the horizon of my exciting and ever-changing field.