Mass Spectrometry

TLC-MS is here and still evolving – continual advances in coupling techniques and ambient mass spectrometry are giving rise to a renaissance. Here, we share the most promising techniques and open your eyes to the powerful – and flexible – combinations of TLC and MS.

Sitting Down With... Barry Karger, James L. Waters Chair in Analytical Chemistry and Barnett Institute Director at Northeastern University, Massachusetts, USA.

The top 10 reasons to consider an advanced multi-detector SEC system, which incorporates light scattering detectors for the measurement of absolute molecular weight and molecular weight distribution with excellent accuracy.

Monika Dittman (Agilent Technologies) and Fabrice Gritti (Waters) offer a manufacturer point of view on the practical limits of LC.

We must inspire creative minds to keep LC moving forward

At ASMS 2015, GC-Orbitrap™ technology was unleashed onto an expectant analytical community. Here’s the backstory.

Sitting Down With... Ruedi Aebersold, Deputy Head, Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Switzerland

Isotope dilution mass spectrometry analysis highlights effective interdisciplinary collaboration – and its legacy should be at the forefront of modern research.

How to bring better diagnostic tests to the market to benefit patients.

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.