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Techniques & Tools Technology

Computer-aided Chromatography

| Eva Tyteca

We need to extend the limits of gradient condition optimization beyond reversed-phase separations.

Techniques & Tools Genomics & DNA Analysis

Jurassic Park Parchment

| Stephanie Vine

DNA from ancient archive gives researchers a window into animals of the past

Techniques & Tools Spectroscopy

Swimming with Spectroscopy

| Stephanie Vine

Is it time to drop your NIR instrument in the pool?

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Fields & Applications Mass Spectrometry

When Great Minds Think Alike

| Rich Whitworth

The M908 took the top spot in our 2013 Innovation Awards – “Revolutionary technology; will be an inspiration for new generations,” said the judges. Here, four co-founders of 908 Devices describe the perfect storm that led to the creation of the world’s first handheld mass spectrometer.

Techniques & Tools Technology

Return of the TASIAs

| Rich Whitworth

Accurate measurement drives progress in science in immeasurable ways. Here, we celebrate a year’s worth of advances in The Analytical Scientist Innovation Awards 2014. What impact will these 15 TASIA winners have on your field?

Fields & Applications Technology

Outsmarting Ebola While You Sleep

| Rich Whitworth

A new World Community Grid project harnesses excess computational power donated by volunteers to screen millions of candidate drug molecules

Fields & Applications Technology

Miraculous miRNA Disease Detection?

A new microRNA analysis platform aims to detect disease well ahead of symptoms

Techniques & Tools Technology

Two Years On

| Rich Whitworth

Including the contents this final issue of 2014, we’ve published just shy of 350 articles to date, covering all aspects of analytical science.

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