LC-MS/MS Method for the Determination of Diclofenac in Human Plasma
A liquid chromatography-tandem mass spectrometry method for the determination of diclofenac in human plasma was developed, giving good chromatographic peak shape and linearity over the required dynamic range of 1 to 1000 ng/mL.
sponsored by Thermo Fisher Scientific
Table 1: Average precision data for six replicate QCs for diclofenac
Standard | Concentration (ng/mL) | Average Calculated Concentration (n=6) |
Average %Diff |
Average Precision (%CV) | % Recovery |
---|---|---|---|---|---|
Quality Control | 15 | 14.7 | -2 | 4.4 | 86 |