Data Analysis

In this application note, we'll describe the successful molecular weight measurement of a polystyrene, PMMA and PVC sample using the OMNISEC system. This instrument can accurately measure the absolute molecular weight of any polymers independent of elution volume or structure. Although the measurements here have been performed using simple polymers, these methods can be applied to any polymer measured by GPC.

In this white paper we examine the deformulation workflow, demonstrating the value of the technique of Morphologically Directed Raman Spectroscopy (MDRS) within this context. Case studies illustrate the relevance of MDRS data.

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.

How can a metrology project to measure zero help in the goal of cleaner air?

Way back in the mid-1960s, somewhere in the North American Midwest, J. Calvin Giddings spent a sleepless night in a noisy motel room. Even the room’s rattling air-conditioning unit gave him a hard time.

My group is working on several new things for GC×GC right now.

Consider designing the readout first when developing point-of-need assays.

The ageless wisdom, “imitation is the sheerest form of flattery,” once again holds true. Unfortunately in quantitative analysis, imitation comes with real consequences.

There are a plethora of useful software packages available to analytical scientists for processing experimental data and results. At the top of the list – or pretty darn close to the top – is Microsoft Excel. Why?

In some industries, for example, in early-stage pharmaceutical development, it is desirable to measure particle size from a small samples of dry powders. However measuring small quantities risks measuring a sample that is not representative of the bulk material. In this application note, we demonstrate the capability of the Aero S dry dispersion unit and the Mastersizer 3000 to measure small quantities of pharmaceutical materials dosed with large particles and to detect those large, anomalous particles.