Cookies

Like most websites The Analytical Scientist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.

Data Analysis

Techniques & Tools Sample Preparation

Solvent Enhanced Light Scattering Technique Enhances Gel Permeation Chromatography Analysis

| Chris Mirley, Sean Daughtry, Wei Sen Wong

The ideal solvent for a material may not provide a sufficient refractive index difference for light scattering detection. This example of a biodegradable polymer shows how SELS is used to increase dn/dc to give enhanced detection sensitivity

Techniques & Tools Sample Preparation

Measuring Antibody Molecular Weight by SEC-MALS

| Sponsored by Malvern Panalytical

In this application note, a purified polyclonal antibody (IgG) is separated using Size Exclusion Chromatography (SEC) and characterized using the Viscotek SEC-MALS 20, allowing calculation of molecular weight and radius of gyration (Rg).

Techniques & Tools Data Analysis

Rebooting Application Notes

| Rich Whitworth

App notes are undeniably useful, giving you access to expert knowledge in your field or helping you understand a new technique. But what if they went beyond simply providing static information? Enter AppsLab.

Techniques & Tools Metabolomics & Lipidomics

The Trouble with Metabolomics

| Georgios Theodoridis

The pursuit of the metabolome may no longer be a novel field, but it remains the biggest analytical challenge.

Techniques & Tools Sample Preparation

Assessing the effect of formulation composition on spidroin charge and stability

| Sponsored by Malvern Panalytical

This application note describes the use of a Zetasizer Nano ZSP to characterize the charge state of spidroins in different formulations. The earliest stages of spidroin aggregation in different formulations are then assessed using low-temperature synamic light scattering (DLS) thermal trend experiments.

Techniques & Tools Sample Preparation

Case study: Effects of gamma-ray sterilization on high molecular weight

| Baljit Ghatora

A sample of PMMA was analysed by Size Exclusion Chromatography with Triple detection, before and after sterilization. Reduction in the molecular weight was shown to be firstly by cleaving the polymer at the branching points.

Techniques & Tools Sample Preparation

Viscotek SEC-MALS 20 to measure protein aggregation

| Sponsored by Malvern Panalytical

In this application note, a selection of proteins are separated using Size Exclusion Chromatograpghy (SEC). The molecular weights of their oligomers and aggregates are measured by SEC-MALS and the results discussed.

Techniques & Tools Data Analysis

Defying the Data Tsunami

| Lutgarde Buydens

We talk to Lutgarde Buydens, Professor Analytical Chemistry: Chemometrics, Radboud University

Techniques & Tools Spectroscopy

Gurus of Raman Spectroscopy

| Volker Deckert, Duncan Graham

In the light of a disruptive new paper, four experts discuss the future of Raman spectroscopy

Techniques & Tools Liquid Chromatography

Is Your Biomarker Analysis Accurate?

| James Settlage

Time to take the plunge with supercritical fluid chromatography in bioanalytical applications

Newsletter

Send me the latest from The Analytical Scientist.

Sign up now

Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine

Register