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Mass Spectrometry

Techniques & Tools Technology

The Tools of Proteomics

| Norm Dovichi, Amanda Hummon

The proteome, which is the set of proteins expressed by a genome, cell, tissue or organism at a given time ... presents immense analytical challenges – but offers substantial rewards. Here, current approaches to proteomics, their strengths and their shortcomings, are explored.

Fields & Applications Mass Spectrometry

Dried Blood Spot 101

| Sangeeta Tanna, Graham Lawson

Introduced by Robert Guthrie in the 1960s, dried blood spot (DBS) sampling involves taking small drops ... of blood from either a finger prick (or heel prick in neonates) and depositing them on specially manufactured absorbent card where they are allowed to dry. Once dry, DBS cards can be readily transported by post for analysis since the components of the blood remain unchanged for several days, even at room temperature. For analysis, a portion of the blood spot is removed from the card and placed in a solvent to extract the analyte(s) of interest.

Techniques & Tools Mass Spectrometry

Instrumental to Success

| Steve Cohen

An illustration of how working with customers throughout development increases the effectiveness of ... new products.

Techniques & Tools Mass Spectrometry

Family Affair

| Rich Whitworth

Günther Laukien, founder of Bruker Physik AG, posthumously receives 2013 Pittcon Heritage Award ...

Techniques & Tools Mass Spectrometry

Every Dog Has Its Day

| Rich Whitworth

A new “sniff” test for explosives uses direct, real-time vapor detection in a bid to put our canine colleagues ... out of work in the screening of people, baggage and cargo.

Fields & Applications Mass Spectrometry

Spot On

| Sangeeta Tanna, Graham Lawson

Dried Blood Spot (DBS) sampling is being adopted in drug development, paediatric healthcare, and, more recently, patient compliance.

Fields & Applications Mass Spectrometry

Saccharide and Polysaccharide Analysis

| Sponsored by PSS

New column offers significant performance improvements in saccharide and polysaccharide analysis.

Techniques & Tools Mass Spectrometry

Mass App-eal

| Rich Whitworth

A free iPad app allows you to run simulated mass spectrums of gas and vapor species without breaking ...

Fields & Applications Mass Spectrometry

Analysis of polycyclic aromatic hydrocarbons from vehicle exhaust using TD–GC/TOF MS

This Application Note describes how the BenchTOF-dxTM time-of-flight mass spectrometer and TargetViewTM compound identification software can be...

Techniques & Tools Food, Beverage & Agriculture

Regulating Food Allergens

| Lauren Jackson

Current methods to detect food proteins that cause adverse immune response can, and are, being improved ...

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