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Spectroscopy

Techniques & Tools Mass Spectrometry

Clinical Collaborations

| Rich Whitworth

Is analytical science poised to storm the theatre and steal the spotlight? Possibly not. But I do sense an increasingly central – and recognized – role, particularly in the clinic.

Techniques & Tools Sample Preparation

GPC/SEC analysis of polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA) using OMNISEC

| Sponsored by Malvern Panalytical

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

Techniques & Tools Mass Spectrometry

Chromatography: Winning Every Battle, Losing the War?

| Hans-Gerd Janssen

Other techniques are beating chromatography and mass spectrometry to the hero’s reward all too often. Are they better? No. Are they faster to first result? Yes. Is it time to acknowledge that – on the frontlines – fit-for-purpose triumphs over best-in-class? You decide.

Techniques & Tools Liquid Chromatography

Gurus of Chiral Separations

| Christopher J. Welch, Yoshio Okamoto, Bernard Testa, Wolfgang Lindner

In Lewis Carroll’s 1871 novel, Through the Looking-Glass, Alice suggests to her black kitten, “Perhaps Looking-Glass milk isn’t good to drink...” And though our four gurus don’t attempt to predict the potability of milk from a mirror world, they keenly address the broader significance of chirality, the major milestones in chiral analysis, and where the field is heading.

Techniques & Tools Forensics

Adding Science Behind the Canine

| John DeHaan, Gareth S. Dobson, David Matthew

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Techniques & Tools Spectroscopy

Swimming with Spectroscopy

| Stephanie Vine

Is it time to drop your NIR instrument in the pool?

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Techniques & Tools Spectroscopy

For the Love of Spectroscopy

| Nicoló Omenetto

Sitting Down With Nicoló Omenetto, Research Professor in the Department of Chemistry at the University of Florida, USA.

Fields & Applications Mass Spectrometry

When Great Minds Think Alike

| Rich Whitworth

The M908 took the top spot in our 2013 Innovation Awards – “Revolutionary technology; will be an inspiration for new generations,” said the judges. Here, four co-founders of 908 Devices describe the perfect storm that led to the creation of the world’s first handheld mass spectrometer.

Techniques & Tools Technology

Return of the TASIAs

| Rich Whitworth

Accurate measurement drives progress in science in immeasurable ways. Here, we celebrate a year’s worth of advances in The Analytical Scientist Innovation Awards 2014. What impact will these 15 TASIA winners have on your field?

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