Data Analysis

Techniques & Tools Sample Preparation

GPC/SEC analysis of polylactic acid (PLA) and poly(lactic-co-glycolic acid) (PLGA) using OMNISEC

01/28/2015 | Sponsored by Malvern Panalytical

In this application note, a selection of different PLA and PLGA polymer samples were analyzed on Malvern's OMNISEC GPC/SEC system, which combines multiple detectors to provide information about structure and solution properties.

Techniques & Tools Mass Spectrometry

Chromatography: Winning Every Battle, Losing the War?

01/22/2015 | Hans-Gerd Janssen

Other techniques are beating chromatography and mass spectrometry to the hero’s reward all too often. Are they better? No. Are they faster to first result? Yes. Is it time to acknowledge that – on the frontlines – fit-for-purpose triumphs over best-in-class? You decide.

Techniques & Tools Data Analysis

Making Room for Improvement

01/19/2015 | Dennis Åsberg

To make way for more flexible approved analytical methods, we need a better understanding of the underlying scientific principles.

Fields & Applications Data Analysis

DNA Imaging On-the-Go

01/19/2015 | Stephanie Vine

Turn your smartphone into a portable fluorescence microscope for imaging and sizing DNA molecules

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system

12/19/2014

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

12/19/2014

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions. The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates. Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Techniques & Tools Data Analysis

The Champions League of Measurement Science

12/15/2014 | Peter Schoenmakers

A technique can only make it into the upper echelons of analytical chemistry with a strong, balanced team. And that means bringing together fundamental researchers, application specialists, and instrumentation experts on a well-supported playing field.