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Data Analysis

Techniques & Tools Data Analysis

Emphasis on Science

| Ulrich Panne

It is clear that analytical science is interdisciplinary, but what exists at its heart –and how do we instill that in students?

Techniques & Tools Data Analysis

Shrinking Ion-selective Sensors for Success

| Eric Bakker, Xiaojiang Xie

Conventional bulk ion-selective sensors have been extensively studied and are well understood. Now, they must be miniaturized for cutting-edge applications, allowing us to blur the line between sensing and bulk solution chemistry.

Fields & Applications Technology

Characterization of hydrodynamic changes upon cation-binding to proteins

Work performed in conjunction with the Institut Pasteur, Paris, France Cations are specifically recognized by numerous proteins. Despite their small size, their specific interactions with highly charged residues allow them to induce significant conformational changes on their binding proteins.

Fields & Applications Sample Preparation

Characterization of Whey Protein Isolate (WPI) using multi-detector size-exclusion chromatography

Whey is a by-product of the cheese-making process, and Whey Protein Isolate (WPI) is a dietary supplement and food ingredient created by separating components from milk. It contains a high percentage of pure protein and can be pure enough to be virtually lactose free, carbohydrate free, fat free, and cholesterol free. In this application note, a sample of WPI was characterized using the Viscotek TDAmax. The 4 main components in this mixture were separated and individually characterized.

Fields & Applications Sample Preparation

Applications of Isothermal Titration Calorimetry and differential scanning calorimetry in biopharmaceutical

This application note presents an example of how calorimetry aided the formulation development for ProX by providing insight into excipient-protein interactions. Polysorbate-80 and phenol are examined here as potential additives to the formulation buffer for ProX.

Fields & Applications Technology

Exosomes and Microvesicles: An introduction

The study of exosomes and other cell-derived microvesicles is an area of rapidly rowing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This document shows the degree to which the technique of Nanoparticle Tracking Analysis (NTA) is helping to address these problems.

Fields & Applications Sample Preparation

Beyond SOPs – Exploring the Rigor and Requirements of Analytical QbD

Analytical QbD (AQbD) promises to extend the rigor and benefits of QbD into the area of analytical method development.

Techniques & Tools Mass Spectrometry

Extreme Environments

Over the past few months, we’ve been asking you to send in the photos and images that best reflect the important and intriguing work that you do.

Techniques & Tools Food, Beverage & Agriculture

Tea With Rich...

| Rich Whitworth

Whilst at Riva 2014 (the 38th ISCC and 11th GCxGC Symposium), Rich Whitworth, editor of The Analytical Scientist, invited three key participants of the conference to take part in an exciting new video projec

Fields & Applications Sample Preparation

10 Reasons that the Zetasizer Nano is chosen for scientific success

New components and measurement techniques continue to be introduced for the Zetasizer Nano. New to the system are a Surface Zeta Potential accessory and a new diffusion barrier method for improved zeta potential measurements of protein samples. Why is the Malvern Zetasizer Nano so popular and found in a broad range of applied and fundamental scientifi c projects across all industries and fields? Because, it is simply the most dynamic and broad ranged instrument on the market for solving technical issues in today’s research environment and it continues to evolve with new capabilities. Here are 10 reasons why you should choose the Zetasizer Nano:

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